UniProt P67870
Casein kinase II subunit beta (P67870)
Casein kinase II subunit beta (UniProt P67870), EC 2.7.1.37: 18 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 152 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P67870
- Protein
- Casein kinase II subunit beta
- EC
- 2.7.1.37
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 152 · 18 records with a druggable one
Structures
19 records of P67870 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DS5 | Dimeric crystal structure of the alpha subunit in complex with two beta peptides mimicking the… | x-ray diffraction | E, F, G, H | — | 8 (best 0.86) |
| 1DS5 | Dimeric crystal structure of the alpha subunit in complex with two beta peptides mimicking the… | x-ray diffraction | E, F, G, H | — | 8 (best 0.86) |
| 1JWH | Crystal Structure of Human Protein Kinase CK2 Holoenzyme | x-ray diffraction | C, D | PO4, ZN | 9 (best 0.75) |
| 1JWH | Crystal structure of human protein kinase CK2 holoenzyme | x-ray diffraction | C, D | PO4, ZN | 9 (best 0.75) |
| 1QF8 | Truncated form of casein kinase II beta subunit (2-182) from homo sapiens | x-ray diffraction | A, B | ZN, MG | 1 (best 0.59) |
| 1QF8 | Truncated form of casein kinase II beta subunit (2-182) from homo sapiens | x-ray diffraction | A, B | ZN, MG | 1 (best 0.59) |
| 3EED | Crystal structure of human protein kinase CK2 regulatory subunit (CK2beta; mutant 1-193) | x-ray diffraction | A, B | ZN, SO4 | 6 (best 0.56) |
| 3EED | Crystal structure of human protein kinase CK2 regulatory subunit (CK2BETA; mutant 1-193) | x-ray diffraction | A, B | ZN, SO4 | 6 (best 0.56) |
| 4DGL | Crystal Structure of the CK2 Tetrameric Holoenzyme | x-ray diffraction | A, B | ZN | 6 (best 0.74) |
| 4DGL | Crystal structure of the CK2 tetrameric holoenzyme | x-ray diffraction | A, B | ZN | 6 (best 0.74) |
| 4MD7 | Crystal Structure of full-length symmetric CK2 holoenzyme | x-ray diffraction | A, B, C, D | ZN | 15 (best 0.72) |
| 4MD7 | Crystal structure of full-length symmetric CK2 holoenzyme | x-ray diffraction | A, B, C, D | ZN | 15 (best 0.72) |
| 4MD8 | Crystal Structure of full-length symmetric CK2 holoenzyme with mutated alpha subunit (F121E) | x-ray diffraction | A, B, C, D | ZN | 13 (best 0.73) |
| 4MD8 | Crystal structure of full-length symmetric CK2 holoenzyme with mutated alpha subunit (F121E) | x-ray diffraction | A, B, C, D | ZN | 13 (best 0.73) |
| 4MD9 | Crystal Structure of symmetric CK2 holoenzyme with mutated alpha subunit (F121E truncated at aa 336) | x-ray diffraction | A, B, C, D, I, J, N, O | ZN | 11 (best 0.85) |
| 4MD9 | Crystal structure of symmetric CK2 holoenzyme with mutated alpha subunit (F121E truncated at aa 336) | x-ray diffraction | A, B, C, D, I, J, N, O | ZN | 11 (best 0.85) |
| 4NH1 | Crystal structure of a heterotetrameric CK2 holoenzyme complex carrying the Andante-mutation in… | x-ray diffraction | C, D | ZN | 7 (best 0.73) |
| 4NH1 | Crystal structure of a heterotetrameric CK2 holoenzyme complex carrying the andante-mutation in… | x-ray diffraction | C, D | ZN | 7 (best 0.73) |
| P67870 | AlphaFold monomer V2.0 prediction for casein kinase II subunit beta (P67870) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1QF8 chain B against the predicted model P67870: TM-score 0.99, RMSD 0.42 Å
- 1QF8 chain B against the predicted model P67870: TM-score 0.99, RMSD 0.42 Å
- 3EED chain A against the predicted model P67870: TM-score 0.99, RMSD 0.61 Å
- 3EED chain A against the predicted model P67870: TM-score 0.99, RMSD 0.61 Å
- 1QF8 chain A against the predicted model P67870: TM-score 0.98, RMSD 0.88 Å
- 1QF8 chain A against the predicted model P67870: TM-score 0.98, RMSD 0.88 Å
- 3EED chain B against the predicted model P67870: TM-score 0.98, RMSD 0.70 Å
- 3EED chain B against the predicted model P67870: TM-score 0.98, RMSD 0.70 Å
- 4MD8 chain A against the predicted model P67870: TM-score 0.96, RMSD 1.59 Å
- 4MD8 chain A against the predicted model P67870: TM-score 0.96, RMSD 1.59 Å
Elsewhere
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