UniProt P63756
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (P63756)
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (UniProt P63756), EC 2.7.8.5: 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 9 pockets. Binding sites, druggability and experiment…
- UniProt
- P63756
- Protein
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
- EC
- 2.7.8.5
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 9 · 3 records with a druggable one
Structures
5 records of P63756 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DRJ | Crystal structure of phosphatidylglycerol phosphate synthase in complex with phosphatidylglycerol… | x-ray diffraction | A, B | PO9, ZN | 3 (best 0.77) |
| 7DRJ | Crystal structure of phosphatidylglycerol phosphate synthase in complex with phosphatidylglycerol… | x-ray diffraction | A, B | PO9, ZN | — |
| 7DRK | Crystal structure of phosphatidylglycerol phosphate synthase in complex with cytidine… | x-ray diffraction | A, B | ZN, 58A, G3P | 5 (best 0.71) |
| 7DRK | Crystal structure of phosphatidylglycerol phosphate synthase in complex with cytidine… | x-ray diffraction | A, B | ZN, 58A, G3P | — |
| P63756 | AlphaFold monomer V2.0 prediction for cdp-diacylglycerol-- glycerol-3-phosphate… | predicted | A | — | 1 (best 0.62) |
Ligands
- ZN · Zinc ion · in 4 records
- 58A · 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9e)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy) phosphoryl]cytidine · in 2 records
- G3P · Sn-glycerol-3-phosphate · in 2 records
- PO9 · [(2R)-2-hexadecanoyloxy-3-[oxidanyl-[(2S)-2-oxidanyl-3-phosphonooxy-propoxy]phosphoryl]oxy-propyl] (Z)-octadec-9-enoate · in 2 records
Experiment against prediction
- 7DRJ chain A against the predicted model P63756: TM-score 0.90, RMSD 1.83 Å
- 7DRJ chain A against the predicted model P63756: TM-score 0.90, RMSD 1.83 Å
- 7DRK chain A against the predicted model P63756: TM-score 0.90, RMSD 1.88 Å
- 7DRK chain A against the predicted model P63756: TM-score 0.90, RMSD 1.88 Å
- 7DRJ chain B against the predicted model P63756: TM-score 0.89, RMSD 1.95 Å
- 7DRJ chain B against the predicted model P63756: TM-score 0.89, RMSD 1.95 Å
- 7DRK chain B against the predicted model P63756: TM-score 0.89, RMSD 2.02 Å
- 7DRK chain B against the predicted model P63756: TM-score 0.89, RMSD 2.02 Å
Elsewhere
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