UniProt P63213
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (P63213)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (UniProt P63213): 16 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P63213
- Protein
- Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 22 · 8 records with a druggable one
Structures
17 records of P63213 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6RMV | The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer | x-ray diffraction | B | — | 2 (best 0.43) |
| 6RMV | The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer | x-ray diffraction | B | — | — |
| 7PIV | Active Melanocortin-4 receptor (MC4R)- Gs protein complex bound to agonist NDP-alpha-MSH at 2.86 A… | electron microscopy | G | — | 1 (best 0.73) |
| 7PIV | Active melanocortin-4 receptor (MC4R)- gs protein complex bound to agonist ndp-alpha-msh at 2.86 a… | electron microscopy | G | — | — |
| 7Y12 | Cryo-EM structure of MrgD-Gi complex with beta-alanine | electron microscopy | C | — | 2 (best 0.81) |
| 7Y12 | Cryo-EM structure of mrgd-gi complex with beta-alanine | electron microscopy | C | — | — |
| 7Y15 | Cryo-EM structure of apo-state MrgD-Gi complex | electron microscopy | C | — | 2 (best 0.82) |
| 7Y15 | Cryo-EM structure of apo-state mrgd-gi complex | electron microscopy | C | — | — |
| 8IHB | Cryo-EM structure of HCA2-Gi complex with GSK256073 | electron microscopy | C | — | 1 (best 0.35) |
| 8IHF | Cryo-EM structure of HCA2-Gi complex with MK6892 | electron microscopy | C | — | 2 (best 0.81) |
| 8IHH | Cryo-EM structure of HCA2-Gi complex with LUF6283 | electron microscopy | C | — | 1 (best 0.81) |
| 8IHI | Cryo-EM structure of HCA2-Gi complex with acifran | electron microscopy | C | — | 1 (best 0.42) |
| 8IHJ | Cryo-EM structure of HCA3-Gi complex with acifran | electron microscopy | C | — | 1 (best 0.32) |
| 9IZF | Cryo-EM structure of LPA1-Gi complex with LPA | electron microscopy | C | — | 4 (best 0.81) |
| 9IZG | Cryo-EM structure of LPA1-Gq complex with LPA | electron microscopy | C | — | 3 (best 0.81) |
| 9IZH | Cryo-EM structure of LPA1-G13 complex with LPA | electron microscopy | C | — | 2 (best 0.82) |
| P63213 | AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit… | predicted | A | — | — |
Experiment against prediction
- 7Y15 chain C against the predicted model P63213: TM-score 0.94, RMSD 0.72 Å
- 7Y15 chain C against the predicted model P63213: TM-score 0.94, RMSD 0.72 Å
- 9IZG chain C against the predicted model P63213: TM-score 0.93, RMSD 0.69 Å
- 8IHF chain C against the predicted model P63213: TM-score 0.93, RMSD 0.77 Å
- 8IHH chain C against the predicted model P63213: TM-score 0.93, RMSD 0.77 Å
- 6RMV chain B against the predicted model P63213: TM-score 0.93, RMSD 0.83 Å
- 6RMV chain B against the predicted model P63213: TM-score 0.93, RMSD 0.83 Å
- 8IHI chain C against the predicted model P63213: TM-score 0.93, RMSD 0.80 Å
- 9IZF chain C against the predicted model P63213: TM-score 0.92, RMSD 0.83 Å
- 8IHB chain C against the predicted model P63213: TM-score 0.92, RMSD 0.84 Å
Elsewhere
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