UniProt P62874
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (P62874)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (UniProt P62874): 15 experimental structures and 1 predicted model on GenesisL1, 53 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P62874
- Protein
- Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
- Experimental structures
- 15
- Predicted models
- 1
- Pockets
- 53 · 10 records with a druggable one
Structures
16 records of P62874 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6K41 | cryo-EM structure of alpha2BAR-GoA complex | electron microscopy | B | — | 5 (best 0.83) |
| 6K41 | Cryo-EM structure of ALPHA2BAR-goa complex | electron microscopy | B | — | — |
| 6K42 | cryo-EM structure of alpha2BAR-Gi1 complex | electron microscopy | B | — | 7 (best 0.83) |
| 6K42 | Cryo-EM structure of ALPHA2BAR-GI1 complex | electron microscopy | B | — | — |
| 6RMV | The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer | x-ray diffraction | A | — | 3 (best 0.80) |
| 6RMV | The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer | x-ray diffraction | A | — | — |
| 7Y12 | Cryo-EM structure of MrgD-Gi complex with beta-alanine | electron microscopy | B | — | 5 (best 0.81) |
| 7Y12 | Cryo-EM structure of mrgd-gi complex with beta-alanine | electron microscopy | B | — | — |
| 7Y15 | Cryo-EM structure of apo-state MrgD-Gi complex | electron microscopy | B | — | 5 (best 0.82) |
| 7Y15 | Cryo-EM structure of apo-state mrgd-gi complex | electron microscopy | B | — | — |
| 8IHB | Cryo-EM structure of HCA2-Gi complex with GSK256073 | electron microscopy | B | — | 6 (best 0.81) |
| 8IHF | Cryo-EM structure of HCA2-Gi complex with MK6892 | electron microscopy | B | — | 6 (best 0.81) |
| 8IHH | Cryo-EM structure of HCA2-Gi complex with LUF6283 | electron microscopy | B | — | 5 (best 0.81) |
| 8IHI | Cryo-EM structure of HCA2-Gi complex with acifran | electron microscopy | B | — | 6 (best 0.80) |
| 8IHJ | Cryo-EM structure of HCA3-Gi complex with acifran | electron microscopy | B | — | 5 (best 0.82) |
| P62874 | AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit… | predicted | A | — | — |
Experiment against prediction
- 6K41 chain B against the predicted model P62874: TM-score 1.00, RMSD 0.42 Å
- 6K41 chain B against the predicted model P62874: TM-score 1.00, RMSD 0.42 Å
- 8IHF chain B against the predicted model P62874: TM-score 1.00, RMSD 0.47 Å
- 8IHH chain B against the predicted model P62874: TM-score 1.00, RMSD 0.48 Å
- 8IHB chain B against the predicted model P62874: TM-score 0.99, RMSD 0.48 Å
- 7Y15 chain B against the predicted model P62874: TM-score 0.99, RMSD 0.48 Å
- 7Y15 chain B against the predicted model P62874: TM-score 0.99, RMSD 0.48 Å
- 8IHI chain B against the predicted model P62874: TM-score 0.99, RMSD 0.49 Å
- 7Y12 chain B against the predicted model P62874: TM-score 0.99, RMSD 0.49 Å
- 7Y12 chain B against the predicted model P62874: TM-score 0.99, RMSD 0.49 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.