UniProt P62508
P62508
P62508 (UniProt P62508): 46 experimental structures and 1 predicted model on GenesisL1, 11 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62508
- Experimental structures
- 46
- Predicted models
- 1
- Ligands
- 11
Structures
47 records of P62508 in the MolNFT archive: 46 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KV6 | X-ray structure of the orphan nuclear receptor ERR3 ligand-binding domain in the constitutively… | x-ray diffraction | A, B | — | — |
| 1KV6 | X-ray structure of the orphan nuclear receptor ERR3 ligand- binding domain in the constitutively… | x-ray diffraction | A, B | — | — |
| 1TFC | Crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex… | x-ray diffraction | A, B | — | — |
| 1TFC | Crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex… | x-ray diffraction | A, B | — | — |
| 2E2R | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with… | x-ray diffraction | A | — | — |
| 2E2R | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with… | x-ray diffraction | A | — | — |
| 2EWP | Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domaind with tamoxifen… | x-ray diffraction | A, B, C, D, E | — | — |
| 2EWP | Crystal structure of estrogen related receptor-3 (err-gamma) ligand binding domaind with tamoxifen… | x-ray diffraction | A, B, C, D, E | — | — |
| 2GP7 | Estrogen Related Receptor-gamma ligand binding domain | x-ray diffraction | A, B, C, D | — | — |
| 2GP7 | Estrogen related receptor-gamma ligand binding domain | x-ray diffraction | A, B, C, D | — | — |
| 2GPO | Estrogen Related Receptor-gamma ligand binding domain complexed with a synthetic peptide from RIP140 | x-ray diffraction | A | — | — |
| 2GPO | Estrogen related receptor-gamma ligand binding domain complexed with a synthetic peptide from RIP140 | x-ray diffraction | A | — | — |
| 2GPP | Estrogen Related Receptor-gamma ligand binding domain complexed with a RIP140 peptide and synthetic… | x-ray diffraction | A, B | — | — |
| 2GPP | Estrogen related receptor-gamma ligand binding domain complexed with a RIP140 peptide and synthetic… | x-ray diffraction | A, B | — | — |
| 2GPU | Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen | x-ray diffraction | A | — | — |
| 2GPU | Estrogen related receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen | x-ray diffraction | A | — | — |
| 2GPV | Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen and a SMRT… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2GPV | Estrogen related receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen and a smrt… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2P7A | Crystal Structure of Estrogen Related Receptor g in complex with 3-methyl phenol | x-ray diffraction | A | — | — |
| 2P7A | Crystal structure of estrogen related receptor G in complex with 3- methyl phenol | x-ray diffraction | A | — | — |
| 2P7G | X-ray Structure of Estrogen Related Receptor g in complex with Bisphenol A. | x-ray diffraction | A | — | — |
| 2P7G | X-ray structure of estrogen related receptor G in complex with bisphenol a. | x-ray diffraction | A | — | — |
| 2P7Z | Estrogen Related Receptor Gamma in complex with 4-hydroxy-tamoxifen | x-ray diffraction | A | — | — |
| 2P7Z | Estrogen related receptor gamma in complex with 4-hydroxy- tamoxifen | x-ray diffraction | A | — | — |
| 2ZAS | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with… | x-ray diffraction | A | — | — |
| 2ZAS | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with… | x-ray diffraction | A | — | — |
| 2ZBS | Crystal structure of human estrogen-related receptor gamma ligand binding domain apo form | x-ray diffraction | A | — | — |
| 2ZBS | Crystal structure of human estrogen-related receptor gamma ligand binding domain apo form | x-ray diffraction | A | — | — |
| 2ZKC | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with… | x-ray diffraction | A | — | — |
| 2ZKC | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with… | x-ray diffraction | A | — | — |
| 5YSO | Crystal structure of estrogen related receptor-3 (err-gamma) ligand binding domain with DN200434 | x-ray diffraction | A, B, C | 90C | — |
| 6A6K | Crystal structure of Estrogen-related Receptor-3 (ERR-gamma) ligand binding domain with DN201000 | x-ray diffraction | A, B, C | 9S6 | — |
| 6A6K | Crystal structure of estrogen-related receptor-3 (err-gamma) ligand binding domain with DN201000 | x-ray diffraction | A, B, C | 9S6 | — |
| 6I61 | Crystal structure of human ERRg LBD in complex with bisphenol-B | x-ray diffraction | A | H3W | — |
| 6I61 | Crystal structure of human errg lbd in complex with bisphenol-B | x-ray diffraction | A | H3W | — |
| 6I62 | Crystal structure of human errg lbd in complex with hpte | x-ray diffraction | A | 27N | — |
| 6I63 | Crystal structure of human ERRg LBD in complex with bisphenol-A | x-ray diffraction | A | 2OH | — |
| 6I63 | Crystal structure of human errg lbd in complex with bisphenol-a | x-ray diffraction | A | 2OH | — |
| 6I64 | Crystal structure of human errg lbd in complex with bisphenol-E | x-ray diffraction | A | H48 | — |
| 6I65 | Crystal structure of human errg lbd in complex with 4-iso-propylphenol | x-ray diffraction | A | H3Z | — |
| 6I66 | Crystal structure of human errg lbd in complex with 4-sec-butylphenol | x-ray diffraction | A | H4Q | — |
| 6I67 | Crystal structure of human errg lbd in complex with tetrahydro-2- naphtol | x-ray diffraction | A | H42 | — |
| 6K3N | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with… | x-ray diffraction | A | CW6 | — |
| 6K3N | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with… | x-ray diffraction | A | CW6 | — |
| 6KNR | Crystal structure of Estrogen-related receptor gamma ligand-binding domain with DN200699 | x-ray diffraction | A, B | DL9 | — |
| 6KNR | Crystal structure of estrogen-related receptor gamma ligand-binding domain with DN200699 | x-ray diffraction | A, B | DL9 | — |
| P62508 | AlphaFold monomer V2.0 prediction for estrogen-related receptor gamma (P62508) | predicted | A | — | — |
Ligands
- 2OH · 4,4'-propane-2,2-diyldiphenol · in 2 records
- 9S6 · 3-[(~{E})-5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol · in 2 records
- CW6 · 2-fluoranyl-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol · in 2 records
- DL9 · (E)-4-(1-(4-(1-cyclopropylpiperidin-4-yl)phenyl)-5-hydroxy-2-phenylpent-1-en-1-yl)phenol · in 2 records
- H3W · bisphenol-B · in 2 records
- 27N · 4,4'-(2,2,2-trichloroethane-1,1-diyl)diphenol · in 1 record
- 90C · 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol · in 1 record
- H3Z · 4-propan-2-ylphenol · in 1 record
- H42 · 5,6,7,8-tetrahydronaphthalen-2-ol · in 1 record
- H48 · 4-[1-(4-hydroxyphenyl)ethyl]phenol · in 1 record
- H4Q · 4-[(2~{R})-butan-2-yl]phenol · in 1 record
Experiment against prediction
- 2GP7 chain C against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
- 2GP7 chain C against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
- 2GP7 chain A against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
- 2GP7 chain A against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
- 2GP7 chain B against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
- 2GP7 chain B against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
- 1KV6 chain A against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
- 1KV6 chain A against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
- 2GP7 chain D against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
- 2GP7 chain D against the predicted model P62508: TM-score 0.99, RMSD 0.45 Å
Elsewhere
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