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UniProt P61916

NPC intracellular cholesterol transporter 2 (P61916)

NPC intracellular cholesterol transporter 2 (UniProt P61916): 5 experimental structures on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P61916
Protein
NPC intracellular cholesterol transporter 2
Experimental structures
5
Predicted models
0
Ligands
3
Pockets
2 · 1 record with a druggable one

Structures

5 records of P61916 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5KWYStructure of human NPC1 middle lumenal domain bound to NPC2x-ray diffractionC, DNAG, C3S—
5KWYStructure of human NPC1 middle lumenal domain bound to NPC2x-ray diffractionC, DNAG, C3S—
6W5VNPC1-NPC2 complex structure at pH 5.5electron microscopyDNAG, CLR2 (best 0.80)
6W5VNPC1-NPC2 complex structure at pH 5.5electron microscopyDNAG, CLR—
P61916AlphaFold monomer V2.0 prediction for npc intracellular cholesterol transporter 2 (P61916)———

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
  • C3S · Cholest-5-en-3-yl hydrogen sulfate · in 2 records
  • CLR · Cholesterol · in 2 records

Elsewhere

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