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UniProt P61803

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (P61803)

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (UniProt P61803): 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 16 pockets. Binding sites, druggability and experiment…

UniProt
P61803
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
Experimental structures
6
Predicted models
1
Ligands
3
Pockets
16 · 4 records with a druggable one

Structures

7 records of P61803 in the MolNFT archive: 6 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6S7OCryo-EM structure of human oligosaccharyltransferase complex OST-Aelectron microscopyDKZB, EGY5 (best 0.73)
6S7OCryo-EM structure of human oligosaccharyltransferase complex ost-aelectron microscopyDKZB, EGY—
6S7TCryo-EM structure of human oligosaccharyltransferase complex OST-Belectron microscopyDEGY, KZB4 (best 0.73)
6S7TCryo-EM structure of human oligosaccharyltransferase complex ost-Belectron microscopyDEGY, KZB—
8B6LSubtomogram average of the human Sec61-TRAP-OSTA-transloconelectron microscopyM—3 (best 0.75)
8PN9Structure of human oligosaccharyltransferase OST-A complex bound to NGI-1electron microscopyDGLC, EGY4 (best 0.78)
P61803AlphaFold monomer V2.0 prediction for dolichyl- diphosphooligosaccharide--protein…predictedA——

Ligands

  • EGY · (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium · in 5 records
  • KZB · (2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S}, 9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13, 18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol · in 4 records
  • GLC · alpha-D-glucopyranose · in 1 record

Experiment against prediction

Elsewhere

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