UniProt P61157
Actin-related protein 3 (P61157)
Actin-related protein 3 (UniProt P61157): 41 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P61157
- Protein
- Actin-related protein 3
- Experimental structures
- 41
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 10 · 2 records with a druggable one
Structures
42 records of P61157 in the MolNFT archive: 41 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1K8K | Crystal Structure of Arp2/3 Complex | x-ray diffraction | A | — | — |
| 1K8K | Crystal structure of ARP2/3 complex | x-ray diffraction | A | — | — |
| 1TYQ | Crystal structure of Arp2/3 complex with bound ATP and calcium | x-ray diffraction | A | — | — |
| 1TYQ | Crystal structure of ARP2/3 complex with bound ATP and calcium | x-ray diffraction | A | — | — |
| 1U2V | Crystal structure of Arp2/3 complex with bound ADP and calcium | x-ray diffraction | A | — | — |
| 1U2V | Crystal structure of ARP2/3 complex with bound ADP and calcium | x-ray diffraction | A | — | — |
| 2P9I | Crystal Structure of bovine Arp2/3 Complex co-crystallized with ADP and crosslinked with… | x-ray diffraction | A | — | — |
| 2P9I | Crystal structure of bovine ARP2/3 complex co-crystallized with ADP and crosslinked with… | x-ray diffraction | A | — | — |
| 2P9K | Crystal structure of bovine Arp2/3 complex co-crystallized with ATP and crosslinked with… | x-ray diffraction | A | — | — |
| 2P9K | Crystal structure of bovine ARP2/3 complex co-crystallized with ATP and crosslinked with… | x-ray diffraction | A | — | — |
| 2P9L | Crystal Structure of bovine Arp2/3 complex | x-ray diffraction | A | — | — |
| 2P9L | Crystal structure of bovine ARP2/3 complex | x-ray diffraction | A | — | — |
| 2P9N | Crystal Structure of bovine Arp2/3 complex co-crystallized with ADP | x-ray diffraction | A | — | — |
| 2P9N | Crystal structure of bovine ARP2/3 complex co-crystallized with ADP | x-ray diffraction | A | — | — |
| 2P9P | Crystal Structure of bovine Arp2/3 complex co-crystallized with ADP | x-ray diffraction | A | — | — |
| 2P9P | Crystal structure of bovine ARP2/3 complex co-crystallized with ADP | x-ray diffraction | A | — | — |
| 2P9S | Structure of bovine Arp2/3 complex co-crystallized with ATP/Mg2+ | x-ray diffraction | A | — | — |
| 2P9S | Structure of bovine ARP2/3 complex co-crystallized with ATP/MG2+ | x-ray diffraction | A | — | — |
| 2P9U | Crystal structure of bovine Arp2/3 complex co-crystallized with AMP-PNP and calcium | x-ray diffraction | A | — | — |
| 2P9U | Crystal structure of bovine ARP2/3 complex co-crystallized with AMP- pnp and calcium | x-ray diffraction | A | — | — |
| 3DXK | Structure of Bos Taurus Arp2/3 Complex with Bound Inhibitor CK0944636 | x-ray diffraction | A | — | — |
| 3DXK | Structure of bos taurus ARP2/3 complex with bound inhibitor CK0944636 | x-ray diffraction | A | — | — |
| 3DXM | Structure of Bos taurus Arp2/3 Complex with Bound Inhibitor CK0993548 | x-ray diffraction | A | — | — |
| 3DXM | Structure of bos taurus ARP2/3 complex with bound inhibitor CK0993548 | x-ray diffraction | A | — | — |
| 3RSE | Structural and biochemical characterization of two binding sites for nucleation promoting factor… | x-ray diffraction | A | — | — |
| 3RSE | Structural and biochemical characterization of two binding sites for nucleation promoting factor… | x-ray diffraction | A | — | — |
| 3UKR | Crystal structure of Bos taurus Arp2/3 complex with bound inhibitor CK-666 | x-ray diffraction | A | — | — |
| 3UKR | Crystal structure of bos taurus ARP2/3 complex with bound inhibitor ck-666 | x-ray diffraction | A | — | — |
| 3UKU | Structure of Arp2/3 complex with bound inhibitor CK-869 | x-ray diffraction | A | — | — |
| 3UKU | Structure of ARP2/3 complex with bound inhibitor ck-869 | x-ray diffraction | A | — | — |
| 3ULE | Structure of Bos taurus Arp2/3 complex with bound inhibitor CK-869 and ATP | x-ray diffraction | A | — | — |
| 3ULE | Structure of bos taurus ARP2/3 complex with bound inhibitor ck-869 and ATP | x-ray diffraction | A | — | — |
| 4JD2 | Crystal structure of Bos taurus Arp2/3 complex binding with Mus musculus GMF | x-ray diffraction | A | — | — |
| 4JD2 | Crystal structure of bos taurus ARP2/3 complex binding with mus musculus gmf | x-ray diffraction | A | — | — |
| 4XEI | Orthorhombic isomorph of bovine Arp2/3 complex | x-ray diffraction | A | — | 7 (best 0.84) |
| 4XEI | Orthorhombic isomorph of bovine ARP2/3 complex | x-ray diffraction | A | — | — |
| 4XF2 | Tetragonal structure of ARP2/3 complex | x-ray diffraction | A, T | — | — |
| 6DEC | Crystal structure of bos taurus ARP2/3 complex binding with C-terminus of homo sapiens SPIN90 | x-ray diffraction | A, H | ATP, CA | — |
| 7JPN | Cryo-EM structure of arpin-bound ARP2/3 complex | electron microscopy | A | MG, ATP | — |
| 7TPT | Single-particle Cryo-EM structure of Arp2/3 complex at branched-actin junction. | electron microscopy | A | MG, ADP | 3 (best 0.89) |
| 7TPT | Single-particle cryo-EM structure of ARP2/3 complex at branched-actin junction. | electron microscopy | A | MG, ADP | — |
| P61157 | AlphaFold monomer V2.0 prediction for actin-related protein 3 (P61157) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2P9I chain A against the predicted model P61157: TM-score 0.98, RMSD 1.06 Å
- 2P9I chain A against the predicted model P61157: TM-score 0.98, RMSD 1.06 Å
- 2P9K chain A against the predicted model P61157: TM-score 0.98, RMSD 1.08 Å
- 2P9K chain A against the predicted model P61157: TM-score 0.98, RMSD 1.08 Å
- 2P9S chain A against the predicted model P61157: TM-score 0.98, RMSD 1.15 Å
- 2P9S chain A against the predicted model P61157: TM-score 0.98, RMSD 1.15 Å
- 7JPN chain A against the predicted model P61157: TM-score 0.98, RMSD 1.19 Å
- 2P9P chain A against the predicted model P61157: TM-score 0.98, RMSD 1.17 Å
- 2P9P chain A against the predicted model P61157: TM-score 0.98, RMSD 1.17 Å
- 6DEC chain A against the predicted model P61157: TM-score 0.97, RMSD 1.27 Å
Elsewhere
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