UniProt P60843
Eukaryotic initiation factor 4A-I (P60843)
Eukaryotic initiation factor 4A-I (UniProt P60843), EC 3.6.4.13: 5 experimental structures on GenesisL1, 4 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P60843
- Protein
- Eukaryotic initiation factor 4A-I
- EC
- 3.6.4.13
- Experimental structures
- 5
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 3 · 1 record with a druggable one
Structures
5 records of P60843 in the MolNFT archive: 5 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6XKI | Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog | x-ray diffraction | A | ANP, MG, V6D | — |
| 6XKI | Crystal structure of EIF4A-I in complex with RNA bound to des-mepatea, a pateamine a analog | x-ray diffraction | A | ANP, MG, V6D | — |
| 7DDX | Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1 | x-ray diffraction | B | SO4 | 3 (best 0.53) |
| 7DDX | Crystal structure of KANK1 S1179F mutant in complex wtih EIF4A1 | x-ray diffraction | B | SO4 | — |
| P60843 | AlphaFold monomer V2.0 prediction for eukaryotic initiation factor 4A-I (P60843) | — | — | — |
Ligands
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
- MG · Magnesium ion · in 2 records
- SO4 · Sulfate ion · in 2 records
- V6D · (3S,6Z,8E,11S,15R)-15-amino-3-[(1E,3E,5E)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9, 11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione · in 2 records
Elsewhere
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