UniProt P60753
Lipid A export ATP-binding/permease protein MsbA (P60753)
Lipid A export ATP-binding/permease protein MsbA (UniProt P60753), EC 3.6.3.-: 4 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 22 pockets. Binding sites, druggability and experiment against…
- UniProt
- P60753
- Protein
- Lipid A export ATP-binding/permease protein MsbA
- EC
- 3.6.3.-
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 22 · 2 records with a druggable one
Structures
5 records of P60753 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5TTP | Cryo-EM structure of MsbA-nanodisc with ADP-vanadate | electron microscopy | A, B | — | 14 (best 0.81) |
| 5TTP | Cryo-EM structure of msba-nanodisc with ADP-vanadate | electron microscopy | A, B | — | — |
| 5TV4 | 3D cryo-EM reconstruction of nucleotide-free MsbA in lipid nanodisc | electron microscopy | A, B | PA1, KDO, GMH, PO4, FTT, MYR | — |
| 5TV4 | 3D cryo-EM reconstruction of nucleotide-free msba in lipid nanodisc | electron microscopy | A, B | PA1, KDO, GMH, PO4, FTT, MYR | — |
| P60753 | AlphaFold monomer V2.0 prediction for ATP-dependent lipid a-core flippase (P60753) | predicted | A | — | 8 (best 0.62) |
Ligands
- DAO · Lauric acid · in 2 records
- FTT · 3-hydroxy-tetradecanoic acid · in 2 records
- GMH · L-glycero-alpha-D-manno-heptopyranose · in 2 records
- KDO · 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid · in 2 records
- MYR · Myristic acid · in 2 records
- PA1 · 2-amino-2-deoxy-alpha-D-glucopyranose · in 2 records
- PO4 · Phosphate ion · in 2 records
Experiment against prediction
- 5TV4 chain A against the predicted model P60753: TM-score 0.88, RMSD 3.71 Å
- 5TV4 chain A against the predicted model P60753: TM-score 0.88, RMSD 3.71 Å
- 5TTP chain B against the predicted model P60753: TM-score 0.69, RMSD 5.05 Å
- 5TTP chain A against the predicted model P60753: TM-score 0.69, RMSD 5.05 Å
- 5TTP chain A against the predicted model P60753: TM-score 0.69, RMSD 5.05 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.