UniProt P60469
Liprin-alpha-3 (P60469)
Liprin-alpha-3 (UniProt P60469): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P60469
- Protein
- Liprin-alpha-3
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 2 records with a druggable one
Structures
7 records of P60469 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UWX | Structure of liprin-alpha3 in complex with mDia1 Diaphanous- inhibitory domain | x-ray diffraction | C, D | — | — |
| 4UWX | Structure of liprin-ALPHA3 in complex with MDIA1 diaphanous- inhibitory domain | x-ray diffraction | C, D | — | — |
| 6KIP | Crystal structure of PTPRD phosphatase domain in complex with Liprin-alpha3 tandem SAM domains | x-ray diffraction | B | — | 3 (best 0.73) |
| 6KIP | Crystal structure of ptprd phosphatase domain in complex with liprin- ALPHA3 tandem SAM domains | x-ray diffraction | B | — | — |
| 6KR4 | Crystal structure of the liprin-alpha3_SAM123/LAR_D1D2 complex | x-ray diffraction | E, F, H, G | PO4 | — |
| 6KR4 | Crystal structure of the liprin-ALPHA3_SAM123/LAR_D1D2 complex | x-ray diffraction | E, F, H, G | PO4 | — |
| P60469 | AlphaFold monomer V2.0 prediction for liprin-alpha-3 (P60469) | predicted | A | — | 2 (best 0.71) |
Ligands
- PO4 · Phosphate ion · in 2 records
Experiment against prediction
- 6KIP chain B against the predicted model P60469: TM-score 0.97, RMSD 1.11 Å
- 6KIP chain B against the predicted model P60469: TM-score 0.97, RMSD 1.11 Å
- 6KR4 chain F against the predicted model P60469: TM-score 0.94, RMSD 1.59 Å
- 6KR4 chain F against the predicted model P60469: TM-score 0.94, RMSD 1.59 Å
- 6KR4 chain E against the predicted model P60469: TM-score 0.94, RMSD 1.77 Å
- 6KR4 chain E against the predicted model P60469: TM-score 0.94, RMSD 1.77 Å
- 6KR4 chain H against the predicted model P60469: TM-score 0.93, RMSD 1.86 Å
- 6KR4 chain H against the predicted model P60469: TM-score 0.93, RMSD 1.86 Å
- 4UWX chain C against the predicted model P60469: TM-score 0.90, RMSD 0.17 Å
- 4UWX chain C against the predicted model P60469: TM-score 0.90, RMSD 0.17 Å
Elsewhere
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