UniProt P60033
CD81 antigen (P60033)
CD81 antigen (UniProt P60033): 29 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P60033
- Protein
- CD81 antigen
- Experimental structures
- 29
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 23 · 2 records with a druggable one
Structures
30 records of P60033 in the MolNFT archive: 29 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1G8Q | Crystal structure of human CD81 extracellular domain, a receptor for hepatitis C virus | x-ray diffraction | A, B | — | — |
| 1G8Q | Crystal structure of human CD81 extracellular domain, a receptor for hepatitis C virus | x-ray diffraction | A, B | — | — |
| 1IV5 | New Crystal Form of Human CD81 Large Extracellular Loop. | x-ray diffraction | A, B | — | — |
| 1IV5 | New crystal form of human CD81 large extracellular loop. | x-ray diffraction | A, B | — | — |
| 3X0E | Crystal structure of the ectodomain of human CD81 large extracellular loop (hCD81-LEL) | x-ray diffraction | A, B | — | — |
| 3X0E | Crystal structure of the ectodomain of human CD81 large extracellular loop (HCD81-lel) | x-ray diffraction | A, B | — | — |
| 5DFV | Crystal structure of human CD81 large extracellular loop in complex with murine Fab fragment K04 | x-ray diffraction | A, B | — | — |
| 5DFW | Crystal structure of human CD81 large extracellular loop in complex with single chain fv fragment… | x-ray diffraction | A | — | — |
| 5DFW | Crystal structure of human CD81 large extracellular loop in complex with single chain fv fragment… | x-ray diffraction | A | — | — |
| 5M2C | Structural tuning of CD81LEL (space group P32 1 2) | x-ray diffraction | A, B | PO4 | — |
| 5M2C | Structural tuning of CD81LEL (space group P32 1 2) | x-ray diffraction | A, B | PO4 | — |
| 5M33 | Structural tuning of CD81LEL (space group P21) | x-ray diffraction | A, B | — | — |
| 5M33 | Structural tuning of CD81LEL (space group P21) | x-ray diffraction | A, B | — | — |
| 5M3D | Structural tuning of CD81LEL (space group P31) | x-ray diffraction | A, B, C, D | PO4 | 2 (best 0.40) |
| 5M3D | Structural tuning of CD81LEL (space group P31) | x-ray diffraction | A, B, C, D | PO4 | — |
| 5M3T | Structural tuning of CD81LEL (space group P64) | x-ray diffraction | A, B | CL | — |
| 5M3T | Structural tuning of CD81LEL (space group P64) | x-ray diffraction | A, B | CL | — |
| 5M4R | Structural tuning of CD81LEL (space group C2) | x-ray diffraction | A, B, C, D, E | SO4 | 3 (best 0.37) |
| 5M4R | Structural tuning of CD81LEL (space group C2) | x-ray diffraction | A, B, C, D, E | SO4 | — |
| 5TCX | Crystal structure of human tetraspanin CD81 | x-ray diffraction | A | CLR | — |
| 6EJG | Crystal structure of human CD81 large extracellular loop in complex with single chain fv fragment 4 | x-ray diffraction | A, B | — | 4 (best 0.33) |
| 6EJG | Crystal structure of human CD81 large extracellular loop in complex with single chain fv fragment 4 | x-ray diffraction | A, B | — | — |
| 6EJM | Crystal structure of human CD81 large extracellular loop in complex with single chain fv fragment 5 | x-ray diffraction | A, B | — | 5 (best 0.67) |
| 6EJM | Crystal structure of human CD81 large extracellular loop in complex with single chain fv fragment 5 | x-ray diffraction | A, B | — | — |
| 6EK2 | Crystal structure of human CD81 large extracellular loop in complex with single chain fv fragment 10 | x-ray diffraction | A, B | — | 6 (best 0.45) |
| 6EK2 | Crystal structure of human CD81 large extracellular loop in complex with single chain fv fragment 10 | x-ray diffraction | A, B | — | — |
| 6U9S | Crystal structure of human CD81 large extracellular loop in complex with 5A6 Fab | x-ray diffraction | C, F | — | — |
| 7JIC | Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment | electron microscopy | B | — | 3 (best 0.72) |
| 7JIC | Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment | electron microscopy | B | — | — |
| P60033 | AlphaFold monomer V2.0 prediction for CD81 antigen (P60033) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5TCX chain A against the predicted model P60033: TM-score 0.98, RMSD 0.84 Å
- 5M2C chain A against the predicted model P60033: TM-score 0.96, RMSD 0.77 Å
- 5M2C chain A against the predicted model P60033: TM-score 0.96, RMSD 0.77 Å
- 5M2C chain B against the predicted model P60033: TM-score 0.96, RMSD 0.79 Å
- 5M2C chain B against the predicted model P60033: TM-score 0.96, RMSD 0.79 Å
- 5M4R chain B against the predicted model P60033: TM-score 0.95, RMSD 0.88 Å
- 5M4R chain B against the predicted model P60033: TM-score 0.95, RMSD 0.88 Å
- 5M3D chain A against the predicted model P60033: TM-score 0.94, RMSD 1.28 Å
- 5M3D chain A against the predicted model P60033: TM-score 0.94, RMSD 1.28 Å
- 5M4R chain C against the predicted model P60033: TM-score 0.94, RMSD 0.98 Å
Elsewhere
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