UniProt P58154
Acetylcholine-binding protein (P58154)
Acetylcholine-binding protein (UniProt P58154): 96 experimental structures and 1 predicted model on GenesisL1, 22 ligands bound, 271 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P58154
- Protein
- Acetylcholine-binding protein
- Experimental structures
- 96
- Predicted models
- 1
- Ligands
- 22
- Pockets
- 271 · 14 records with a druggable one
Structures
97 records of P58154 in the MolNFT archive: 96 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1I9B | X-ray structure of acetylcholine binding protein (achbp) | x-ray diffraction | A, B, C, D, E | — | — |
| 1I9B | X-ray structure of acetylcholine binding protein (achbp) | x-ray diffraction | A, B, C, D, E | — | — |
| 1UV6 | X-ray structure of acetylcholine binding protein (AChBP) in complex with carbamylcholine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1UV6 | X-ray structure of acetylcholine binding protein (achbp) in complex with carbamylcholine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1UW6 | X-ray structure of acetylcholine binding protein (AChBP) in complex with nicotine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 1UW6 | X-ray structure of acetylcholine binding protein (achbp) in complex with nicotine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 1UX2 | X-ray structure of acetylcholine binding protein (AChBP) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1UX2 | X-ray structure of acetylcholine binding protein (achbp) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1YI5 | Crystal structure of the a-cobratoxin-AChBP complex | x-ray diffraction | A, B, C, D, E | — | — |
| 1YI5 | Crystal structure of the a-cobratoxin-achbp complex | x-ray diffraction | A, B, C, D, E | — | — |
| 2ZJU | Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein (Ls-AChBP) Complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 2ZJU | Crystal structure of lymnaea stagnalis acetylcholine binding protein (ls-achbp) complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 2ZJV | Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein (Ls-AChBP) Complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 2ZJV | Crystal structure of lymnaea stagnalis acetylcholine binding protein (ls-achbp) complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3U8J | Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex… | x-ray diffraction | B, A, C, D, E, F, G, J, I, H | — | — |
| 3U8J | Crystal structure of the acetylcholine binding protein (achbp) from lymnaea stagnalis in complex… | x-ray diffraction | B, A, C, D, E, F, G, J, I, H | — | — |
| 3U8K | Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3U8K | Crystal structure of the acetylcholine binding protein (achbp) from lymnaea stagnalis in complex… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3U8L | Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3U8L | Crystal structure of the acetylcholine binding protein (achbp) from lymnaea stagnalis in complex… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3U8M | Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3U8M | Crystal structure of the acetylcholine binding protein (achbp) from lymnaea stagnalis in complex… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3U8N | Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3U8N | Crystal structure of the acetylcholine binding protein (achbp) from lymnaea stagnalis in complex… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3WIP | Crystal structure of acetylcholine bound to Ls-AChBP | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3WIP | Crystal structure of acetylcholine bound to ls-achbp | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3WTH | Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTH | Crystal structure of lymnaea stagnalis acetylcholine-binding protein Q55R mutant complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTI | Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTI | Crystal structure of lymnaea stagnalis acetylcholine-binding protein Q55R mutant complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTJ | Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Thiacloprid | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTJ | Crystal structure of lymnaea stagnalis acetylcholine binding protein complexed with thiacloprid | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTK | Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTK | Crystal structure of lymnaea stagnalis acetylcholine-binding protein Q55R mutant complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTL | Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Nitromethylene… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTL | Crystal structure of lymnaea stagnalis acetylcholine binding protein complexed with nitromethylene… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTM | Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTM | Crystal structure of lymnaea stagnalis acetylcholine-binding protein Q55R mutant complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTN | Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3WTN | Crystal structure of lymnaea stagnalis acetylcholine binding protein complexed with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3WTO | Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3WTO | Crystal structure of lymnaea stagnalis acetylcholine-binding protein Q55R mutant complexed with… | x-ray diffraction | A, B, C, D, E | — | — |
| 3ZDG | Crystal Structure of Ls-AChBP complexed with carbamoylcholine analogue 3-(dimethylamino)butyl… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3ZDG | Crystal structure of ls-achbp complexed with carbamoylcholine analogue 3-(DIMETHYLAMINO)BUTYL… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3ZDH | Crystal structure of Ls-AChBP complexed with carbamoylcholine analogue… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3ZDH | Crystal structure of ls-achbp complexed with carbamoylcholine analogue… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4ALX | Crystal Structure of Ls-AChBP complexed with the potent nAChR antagonist DHbE | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4ALX | Crystal structure of ls-achbp complexed with the potent nachr antagonist dhbe | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4NZB | NS9283 bound to Ls-AChBP | x-ray diffraction | G, D, E, A, B, C, F, H, I, J, K, L, M, N, O | — | — |
| 4NZB | NS9283 bound to ls-achbp | x-ray diffraction | G, D, E, A, B, C, F, H, I, J, K, L, M, N, O | — | — |
| 4QAA | X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4QAA | X-ray structure of acetylcholine binding protein (achbp) in complex with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4QAB | X-RAY STRUCTURE of ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4QAB | X-ray structure of acetylcholine binding protein (achbp) in complex with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4QAC | X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4QAC | X-ray structure of acetylcholine binding protein (achbp) in complex with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4UM1 | Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3573 | x-ray diffraction | A, B, C, D, E | — | — |
| 4UM1 | Engineered ls-achbp with ALPHA4-ALPHA4 binding pocket in complex with NS3573 | x-ray diffraction | A, B, C, D, E | — | — |
| 4UM3 | Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3920 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n | — | — |
| 4UM3 | Engineered ls-achbp with ALPHA4-ALPHA4 binding pocket in complex with NS3920 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n | — | — |
37 records more on the page itself.
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 11 records
- PO4 · Phosphate ion · in 5 records
- SO4 · Sulfate ion · in 5 records
- A1LW0 · 2-methyl-1-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine · in 2 records
- CL · Chloride ion · in 2 records
- NH2 · Amino group · in 2 records
- U8T · 6-bromanylspiro[3~{H}-chromene-2,4'-piperidine]-4-one · in 2 records
- 4P6 · (3E)-3-(thiophen-2-ylmethylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine · in 1 record
- 4QW · 3-{(4E)-4-[(1-methyl-1H-imidazol-5-yl)methylidene]-3,4-dihydro-2H-pyrrol-5-yl}pyridine · in 1 record
- 6GF · 6-(4-methoxyphenyl)-N~4~,N~4~-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine · in 1 record
- 6GH · N~4~,N~4~-bis[(pyridin-2-yl)methyl]-6-(thiophen-3-yl)pyrimidine-2,4-diamine · in 1 record
- 6GK · 6-(2-methoxyphenyl)-N~4~,N~4~-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine · in 1 record
- 6GM · 4-(2-amino-6-{bis[(pyridin-2-yl)methyl]amino}pyrimidin-4-yl)phenol · in 1 record
- 7IE · Flupyradifurone · in 1 record
- 7II · Sulfoxaflor · in 1 record
- 7OF · (~{N}~{E})-~{N}-[1-[(6-chloranylpyridin-3-yl)methyl]pyridin-2-ylidene]-2,2,2-tris(fluoranyl)ethanamide · in 1 record
- 8L3 · 3-[[4-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]methoxy]pyridine · in 1 record
- H8U · Paraherquamide A · in 1 record
- PHN · 1,10-phenanthroline · in 1 record
- U8Q · 4-[4-(trifluoromethyl)phenoxy]piperidine · in 1 record
- WCW · 4-azanyl-1-phenyl-piperidine-4-carboxylic acid · in 1 record
- WNO · 2-[(2~{R})-1-ethylimidazolidin-2-yl]-6-pyridin-2-yl-pyridine · in 1 record
Experiment against prediction
- 3U8J chain E against the predicted model P58154: TM-score 1.00, RMSD 0.27 Å
- 3U8J chain E against the predicted model P58154: TM-score 1.00, RMSD 0.27 Å
- 3U8M chain E against the predicted model P58154: TM-score 1.00, RMSD 0.29 Å
- 3U8M chain E against the predicted model P58154: TM-score 1.00, RMSD 0.29 Å
- 3U8J chain F against the predicted model P58154: TM-score 1.00, RMSD 0.30 Å
- 3U8J chain F against the predicted model P58154: TM-score 1.00, RMSD 0.30 Å
- 4UM3 chain j against the predicted model P58154: TM-score 1.00, RMSD 0.30 Å
- 4UM3 chain j against the predicted model P58154: TM-score 1.00, RMSD 0.30 Å
- 3U8M chain Q against the predicted model P58154: TM-score 1.00, RMSD 0.30 Å
- 3U8M chain Q against the predicted model P58154: TM-score 1.00, RMSD 0.30 Å
Elsewhere
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