UniProt P57743
U6 snRNA-associated Sm-like protein LSm3 (P57743)
U6 snRNA-associated Sm-like protein LSm3 (UniProt P57743): 27 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P57743
- Protein
- U6 snRNA-associated Sm-like protein LSm3
- Experimental structures
- 27
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
28 records of P57743 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3BW1 | Crystal structure of homomeric yeast Lsm3 exhibiting novel octameric ring organisation | x-ray diffraction | A, B | — | — |
| 3BW1 | Crystal structure of homomeric yeast LSM3 exhibiting novel octameric ring organisation | x-ray diffraction | A, B | — | — |
| 3JCM | Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP | electron microscopy | d | — | — |
| 3JCM | Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snrnp | electron microscopy | d | — | — |
| 4C8Q | Crystal structure of the yeast Lsm1-7-Pat1 complex | x-ray diffraction | C | — | — |
| 4C8Q | Crystal structure of the yeast LSM1-7-PAT1 complex | x-ray diffraction | C | — | — |
| 4C92 | Crystal structure of the yeast Lsm1-7 complex | x-ray diffraction | C | — | — |
| 4C92 | Crystal structure of the yeast LSM1-7 complex | x-ray diffraction | C | — | — |
| 4M75 | Crystal structure of Lsm1-7 complex | x-ray diffraction | C, J | — | — |
| 4M75 | Crystal structure of LSM1-7 complex | x-ray diffraction | C, J | — | — |
| 4M77 | Crystal structure of Lsm2-8 complex, space group I212121 | x-ray diffraction | C, J | — | — |
| 4M77 | Crystal structure of LSM2-8 complex, space group I212121 | x-ray diffraction | C, J | — | — |
| 4M78 | Crystal structure of Lsm2-8 complex, space group P21 | x-ray diffraction | C, J | — | — |
| 4M78 | Crystal structure of LSM2-8 complex, space group P21 | x-ray diffraction | C, J | — | — |
| 4M7A | Crystal structure of Lsm2-8 complex bound to the 3' end sequence of U6 snRNA | x-ray diffraction | C, J | — | — |
| 4M7A | Crystal structure of LSM2-8 complex bound to the 3' end sequence of U6 snrna | x-ray diffraction | C, J | — | — |
| 4M7D | Crystal structure of Lsm2-8 complex bound to the RNA fragment CGUUU | x-ray diffraction | C, J | — | — |
| 4M7D | Crystal structure of LSM2-8 complex bound to the RNA fragment cguuu | x-ray diffraction | C, J | — | — |
| 4N0A | Crystal structure of Lsm2-3-Pat1C complex from Saccharomyces cerevisiae | x-ray diffraction | A, B, E, F | — | — |
| 4N0A | Crystal structure of LSM2-3-PAT1C complex from saccharomyces cerevisiae | x-ray diffraction | A, B, E, F | — | — |
| 5GAN | The overall structure of the yeast spliceosomal U4/U6.U5 tri-snrnp at 3.7 ångström | electron microscopy | 3 | — | — |
| 5NRL | Structure of a pre-catalytic spliceosome | electron microscopy | 3 | — | — |
| 5VSU | Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA | x-ray diffraction | C | — | — |
| 5VSU | Structure of yeast U6 snrnp with 2'-phosphate terminated U6 RNA | x-ray diffraction | C | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | electron microscopy | r | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström | electron microscopy | r | — | — |
| 6ASO | Structure of yeast U6 snrnp with 3'-phosphate terminated U6 RNA | x-ray diffraction | C | — | — |
| P57743 | AlphaFold monomer V2.0 prediction for U6 snrna-associated sm-like protein LSM3 (P57743) | predicted | A | — | 1 (best 0.40) |
Experiment against prediction
- 4M77 chain C against the predicted model P57743: TM-score 0.98, RMSD 0.41 Å
- 4M77 chain C against the predicted model P57743: TM-score 0.98, RMSD 0.41 Å
- 4M7A chain C against the predicted model P57743: TM-score 0.98, RMSD 0.50 Å
- 4M7A chain C against the predicted model P57743: TM-score 0.98, RMSD 0.50 Å
- 4M7D chain C against the predicted model P57743: TM-score 0.97, RMSD 0.53 Å
- 4M7D chain C against the predicted model P57743: TM-score 0.97, RMSD 0.53 Å
- 3JCM chain d against the predicted model P57743: TM-score 0.97, RMSD 0.53 Å
- 3JCM chain d against the predicted model P57743: TM-score 0.97, RMSD 0.53 Å
- 4M77 chain J against the predicted model P57743: TM-score 0.97, RMSD 0.55 Å
- 4M77 chain J against the predicted model P57743: TM-score 0.97, RMSD 0.55 Å
Elsewhere
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