UniProt P56632
NADH-ubiquinone oxidoreductase chain 4L (P56632)
NADH-ubiquinone oxidoreductase chain 4L (UniProt P56632), EC 1.6.5.3, 7.1.1.2: 85 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 94 pockets. Binding sites, druggability and experiment against…
- UniProt
- P56632
- Protein
- NADH-ubiquinone oxidoreductase chain 4L
- EC
- 1.6.5.3, 7.1.1.2
- Experimental structures
- 85
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 94 · 60 records with a druggable one
Structures
86 records of P56632 in the MolNFT archive: 85 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GPN | Architecture of mammalian respirasome | electron microscopy | i | — | — |
| 5GUP | Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1 | electron microscopy | k | — | 1 (best 0.90) |
| 7V2C | Active state complex I from Q10 dataset | electron microscopy | k | CDL | 1 (best 0.85) |
| 7V2C | Active state complex I from Q10 dataset | electron microscopy | k | CDL | — |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | k | — | 1 (best 0.91) |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | k | — | — |
| 7V2E | Active state complex I from Q10-NADH dataset | electron microscopy | k | CDL | 1 (best 0.91) |
| 7V2E | Active state complex I from Q10-NADH dataset | electron microscopy | k | CDL | — |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | k | — | 1 (best 0.90) |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | k | — | — |
| 7V2H | Active state complex I from DQ-NADH dataset | electron microscopy | k | CDL | 1 (best 0.89) |
| 7V2H | Active state complex I from dq-NADH dataset | electron microscopy | k | CDL | — |
| 7V2K | Deactive state complex I from DQ-NADH dataset | electron microscopy | k | — | 2 (best 0.87) |
| 7V2K | Deactive state complex I from dq-NADH dataset | electron microscopy | k | — | — |
| 7V2R | Active state complex I from Q1-NADH dataset | electron microscopy | k | CDL | 1 (best 0.88) |
| 7V2R | Active state complex I from Q1-NADH dataset | electron microscopy | k | CDL | — |
| 7V30 | Deactive state complex I from Q1-NADH dataset | electron microscopy | k | — | 2 (best 0.91) |
| 7V30 | Deactive state complex I from Q1-NADH dataset | electron microscopy | k | — | — |
| 7V31 | Active state complex I from rote dataset | electron microscopy | k | CDL | 2 (best 0.90) |
| 7V31 | Active state complex I from rotenone dataset | electron microscopy | k | CDL | — |
| 7V32 | Deactive state complex I from rotenone dataset | electron microscopy | k | — | — |
| 7V33 | Active state complex I from rote -NADH dataset | electron microscopy | k | CDL | 1 (best 0.86) |
| 7V33 | Active state complex I from rotenone-NADH dataset | electron microscopy | k | CDL | — |
| 7V3M | Deactive state complex I from rote -NADH dataset | electron microscopy | k | — | — |
| 7V3M | Deactive state complex I from rotenone-NADH dataset | electron microscopy | k | — | — |
| 7VBL | Membrane arm of active state ci from dq-NADH dataset | electron microscopy | k | CDL | — |
| 7VBP | Membrane arm of deactive state CI from DQ-NADH dataset | electron microscopy | k | — | — |
| 7VBP | Membrane arm of deactive state ci from dq-NADH dataset | electron microscopy | k | — | — |
| 7VC0 | Membrane arm of active state CI from Rote -NADH dataset | electron microscopy | k | CDL | 2 (best 0.91) |
| 7VC0 | Membrane arm of active state ci from rotenone-NADH dataset | electron microscopy | k | CDL | — |
| 7VWL | Membrane arm of deactive state CI from rote -NADH dataset | electron microscopy | k | — | 2 (best 0.90) |
| 7VWL | Membrane arm of deactive state ci from rotenone-NADH dataset | electron microscopy | k | — | — |
| 7VXS | Membrane arm of active state CI from Q10 dataset | electron microscopy | k | CDL | 2 (best 0.79) |
| 7VY1 | Membrane arm of deactive state CI from Q10 dataset | electron microscopy | k | — | 2 (best 0.89) |
| 7VY9 | Membrane arm of active state CI from Q10-NADH dataset | electron microscopy | k | CDL | 1 (best 0.91) |
| 7VYE | Membrane arm of deactive state CI from Q10-NADH dataset | electron microscopy | k | — | 3 (best 0.89) |
| 7VYG | Membrane arm of active state CI from rote dataset | electron microscopy | k | CDL | 2 (best 0.84) |
| 7VYS | Membrane arm of active state CI from Q1-NADH dataset | electron microscopy | k | CDL | 4 (best 0.90) |
| 7VZ8 | Membrane arm of deactive state CI from Q1-NADH dataset | electron microscopy | k | — | 2 (best 0.89) |
| 7VZV | Active state CI from Q10 dataset, Subclass 1 | electron microscopy | k | CDL | 1 (best 0.91) |
| 7VZW | Active state CI from Q10 dataset, Subclass 2 | electron microscopy | k | CDL | 1 (best 0.91) |
| 7W00 | Deactive state CI from Q10 dataset, Subclass 1 | electron microscopy | k | — | 1 (best 0.91) |
| 7W0H | Deactive state CI from Q10 dataset, Subclass 2 | electron microscopy | k | — | 1 (best 0.89) |
| 7W0R | Active state CI from Q10-NADH dataset, Subclass 1 | electron microscopy | k | CDL | 3 (best 0.89) |
| 7W0Y | Active state CI from Q10-NADH dataset, Subclass 2 | electron microscopy | k | CDL | 1 (best 0.90) |
| 7W1O | Deactive state CI from Q10-NADH dataset, Subclass 1 | electron microscopy | k | — | 2 (best 0.89) |
| 7W1P | Deactive state CI from Q10-NADH dataset, Subclass 2 | electron microscopy | k | — | 2 (best 0.90) |
| 7W1T | Active state CI from Rote dataset, Subclass 1 | electron microscopy | k | CDL | 1 (best 0.90) |
| 7W1U | Active state CI from Rote dataset, Subclass 2 | electron microscopy | k | — | 1 (best 0.80) |
| 7W1V | Active state CI from Rote -NADH dataset, Subclass 1 | electron microscopy | k | CDL | 1 (best 0.88) |
| 7W1Z | Active state CI from Rote -NADH dataset, Subclass 2 | electron microscopy | k | CDL | 1 (best 0.89) |
| 7W20 | Active state CI from Rote -NADH dataset, Subclass 3 | electron microscopy | k | CDL | — |
| 7W2K | Deactive state CI from Rote -NADH dataset, Subclass 1 | electron microscopy | k | — | 1 (best 0.90) |
| 7W2L | Deactive state CI from Rote -NADH dataset, Subclass 2 | electron microscopy | k | — | 2 (best 0.91) |
| 7W2R | Active state CI from DQ-NADH dataset, Subclass 1 | electron microscopy | k | CDL | — |
| 7W2U | Active state CI from DQ-NADH dataset, Subclass 2 | electron microscopy | k | CDL | — |
| 7W2Y | Active state CI from DQ-NADH dataset, Subclass 3 | electron microscopy | k | CDL | — |
| 7W31 | Deactive state CI from DQ-NADH dataset, Subclass 1 | electron microscopy | k | — | 1 (best 0.90) |
| 7W32 | Deactive state CI from DQ-NADH dataset, Subclass 2 | electron microscopy | k | — | 1 (best 0.90) |
| 7W35 | Deactive state CI from DQ-NADH dataset, Subclass 3 | electron microscopy | k | — | 2 (best 0.89) |
26 records more on the page itself.
Ligands
Experiment against prediction
- 7V2E chain k against the predicted model P56632: TM-score 0.98, RMSD 0.75 Å
- 7V2E chain k against the predicted model P56632: TM-score 0.98, RMSD 0.75 Å
- 7W0R chain k against the predicted model P56632: TM-score 0.98, RMSD 0.75 Å
- 8UD1 chain 1K against the predicted model P56632: TM-score 0.98, RMSD 0.74 Å
- 7VY9 chain k against the predicted model P56632: TM-score 0.98, RMSD 0.77 Å
- 7W0Y chain k against the predicted model P56632: TM-score 0.98, RMSD 0.77 Å
- 8UGI chain 1K against the predicted model P56632: TM-score 0.98, RMSD 0.78 Å
- 8UGN chain 5K against the predicted model P56632: TM-score 0.97, RMSD 0.81 Å
- 7VZ8 chain k against the predicted model P56632: TM-score 0.97, RMSD 0.89 Å
- 8UGJ chain 1K against the predicted model P56632: TM-score 0.97, RMSD 0.81 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.