UniProt P55211
Caspase-9 (P55211)
Caspase-9 (UniProt P55211), EC 3.4.22.62: 14 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P55211
- Protein
- Caspase-9
- EC
- 3.4.22.62
- Experimental structures
- 14
- Predicted models
- 1
Structures
15 records of P55211 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NW9 | Structure of caspase-9 in an inhibitory complex with xiap-BIR3 | x-ray diffraction | B | — | — |
| 1NW9 | Structure of caspase-9 in an inhibitory complex with xiap-BIR3 | x-ray diffraction | B | — | — |
| 2AR9 | Crystal structure of a dimeric caspase-9 | x-ray diffraction | A, B, C, D | — | — |
| 2AR9 | Crystal structure of a dimeric caspase-9 | x-ray diffraction | A, B, C, D | — | — |
| 3D9T | CIAP1-BIR3 in complex with N-terminal peptide from Caspase-9 (ATPFQE) | x-ray diffraction | C, D | — | — |
| 3D9T | CIAP1-BIR3 in complex with N-terminal peptide from caspase- 9 (atpfqe) | x-ray diffraction | C, D | — | — |
| 3V3K | Human caspase 9 in complex with bacterial effector protein | x-ray diffraction | A, C, E, G, I, K, M, O | — | — |
| 3V3K | Human caspase 9 in complex with bacterial effector protein | x-ray diffraction | A, C, E, G, I, K, M, O | — | — |
| 3YGS | Apaf-1 card in complex with prodomain of procaspase-9 | x-ray diffraction | P | — | — |
| 3YGS | Apaf-1 card in complex with prodomain of procaspase-9 | x-ray diffraction | P | — | — |
| 4RHW | Crystal structure of Apaf-1 CARD and caspase-9 CARD complex | x-ray diffraction | E, F | — | — |
| 4RHW | Crystal structure of apaf-1 card and caspase-9 card complex | x-ray diffraction | E, F | — | — |
| 5JUY | Active human apoptosome with procaspase-9 | electron microscopy | O, P, Q, R | — | — |
| 5JUY | Active human apoptosome with procaspase-9 | electron microscopy | O, P, Q, R | — | — |
| P55211 | AlphaFold monomer V2.0 prediction for caspase-9 (P55211) | predicted | A | — | — |
Experiment against prediction
- 3V3K chain G against the predicted model P55211: TM-score 0.99, RMSD 0.71 Å
- 3V3K chain G against the predicted model P55211: TM-score 0.99, RMSD 0.71 Å
- 3V3K chain O against the predicted model P55211: TM-score 0.99, RMSD 0.73 Å
- 3V3K chain O against the predicted model P55211: TM-score 0.99, RMSD 0.73 Å
- 3V3K chain C against the predicted model P55211: TM-score 0.99, RMSD 0.72 Å
- 3V3K chain C against the predicted model P55211: TM-score 0.99, RMSD 0.72 Å
- 3V3K chain K against the predicted model P55211: TM-score 0.99, RMSD 0.74 Å
- 3V3K chain K against the predicted model P55211: TM-score 0.99, RMSD 0.74 Å
- 5JUY chain R against the predicted model P55211: TM-score 0.98, RMSD 0.44 Å
- 5JUY chain R against the predicted model P55211: TM-score 0.98, RMSD 0.44 Å
Elsewhere
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