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UniProt P54888

Delta-1-pyrroline-5-carboxylate synthase B (P54888)

Delta-1-pyrroline-5-carboxylate synthase B (UniProt P54888), EC 1.2.1.41, 2.7.2.11: 4 experimental structures on GenesisL1, 4 ligands bound, 25 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P54888
Protein
Delta-1-pyrroline-5-carboxylate synthase B
EC
1.2.1.41, 2.7.2.11
Experimental structures
4
Predicted models
0
Ligands
4
Pockets
25 · 3 records with a druggable one

Structures

4 records of P54888 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8J0EGK monomer complexes with catalytic intermediateelectron microscopyF, A, B, ETKC, MG2 (best 0.75)
8J0FGK tetramer with adjacent hooks at reaction stateelectron microscopyC, F, A, E, B, G, D, HADP, RGP, MG19 (best 0.88)
8J27GK monomer complexes with ADPelectron microscopyF, A, B, EADP4 (best 0.79)
P54888AlphaFold monomer V2.0 prediction for delta-1-pyrroline-5-carboxylate synthase B (P54888)———

Ligands

  • ADP · Adenosine-5'-diphosphate · in 2 records
  • MG · Magnesium ion · in 2 records
  • RGP · Gamma-glutamyl phosphate · in 1 record
  • TKC · (2~{R})-5-[[[[(2~{R},3~{S},4~{S},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-2-azanyl-5-oxidanylidene-pentanoic acid · in 1 record

Elsewhere

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