UniProt P54708
Potassium-transporting ATPase alpha chain 2 (P54708)
Potassium-transporting ATPase alpha chain 2 (UniProt P54708), EC 7.2.2.13, 7.2.2.19: 3 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 53 pockets. Binding sites, druggability and experiment against…
- UniProt
- P54708
- Protein
- Potassium-transporting ATPase alpha chain 2
- EC
- 7.2.2.13, 7.2.2.19
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 53 · 3 records with a druggable one
Structures
4 records of P54708 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7X22 | Cryo-EM structure of non gastric H,K-ATPase alpha2 K794S in (2K+)E2-AlF state | electron microscopy | A | ALF, MG, K, CLR, PCW | 17 (best 0.76) |
| 7X23 | Cryo-EM structure of non gastric H,K-ATPase alpha2 SPWC mutant in 3Na+E1-AMPPCPF state | electron microscopy | A | ACP, NA | 19 (best 0.84) |
| 7X24 | Cryo-EM structure of non gastric H,K-ATPase alpha2 SPWC mutant in (2K+)E2-AlF state | electron microscopy | A | K, PCW, CLR, ALF, MG | 17 (best 0.72) |
| P54708 | AlphaFold monomer V2.0 prediction for potassium-transporting ATPase alpha chain 2 (P54708) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7X24 chain A against the predicted model P54708: TM-score 0.98, RMSD 1.53 Å
- 7X22 chain A against the predicted model P54708: TM-score 0.98, RMSD 1.56 Å
- 7X23 chain A against the predicted model P54708: TM-score 0.65, RMSD 6.72 Å
Elsewhere
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