UniProt P54623
Centrosomin (P54623)
Centrosomin (UniProt P54623): 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P54623
- Protein
- Centrosomin
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 2 records with a druggable one
Structures
11 records of P54623 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5I7C | Centrosomin-motif 2 (CM2) domain of Drosophila melanogaster Centrosomin (Cnn) | x-ray diffraction | A, B, C, D | ZN | 2 (best 0.61) |
| 5I7C | Centrosomin-motif 2 (CM2) domain of drosophila melanogaster centrosomin (cnn) | x-ray diffraction | A, B, C, D | — | — |
| 5MVW | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila… | x-ray diffraction | A, C, D, B | ZN, CL | — |
| 5MVW | Complex between the leucine zipper (lz) and centrosomin-motif 2 (CM2) domains of drosophila… | x-ray diffraction | A, C, D, B | ZN, CL | — |
| 5MW0 | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila… | x-ray diffraction | A, C, D, B | ZN | — |
| 5MW0 | Complex between the leucine zipper (lz) and centrosomin-motif 2 (CM2) domains of drosophila… | x-ray diffraction | A, C, D, B | ZN | — |
| 5MW9 | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila… | x-ray diffraction | A, B, C, E, F, D, H, G | ZN | — |
| 5MW9 | Complex between the leucine zipper (lz) and centrosomin-motif 2 (CM2) domains of drosophila… | x-ray diffraction | A, B, C, E, F, D, H, G | ZN | — |
| 5MWE | Complex between the Leucine Zipper (LZ, residues 490-567) and Centrosomin-motif 2 (CM2) domains of… | x-ray diffraction | A, C, D, B | ZN, TCE | 1 (best 0.53) |
| 5MWE | Complex between the leucine zipper (lz, residues 490-567) and centrosomin-motif 2 (CM2) domains of… | x-ray diffraction | A, C, D, B | ZN, TCE | — |
| P54623 | AlphaFold monomer V2.0 prediction for centrosomin (P54623) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5MW9 chain G against the predicted model P54623: TM-score 0.95, RMSD 0.57 Å
- 5MW9 chain G against the predicted model P54623: TM-score 0.95, RMSD 0.57 Å
- 5MVW chain D against the predicted model P54623: TM-score 0.94, RMSD 0.59 Å
- 5MVW chain D against the predicted model P54623: TM-score 0.94, RMSD 0.59 Å
- 5MW0 chain D against the predicted model P54623: TM-score 0.93, RMSD 0.72 Å
- 5MW0 chain D against the predicted model P54623: TM-score 0.93, RMSD 0.72 Å
- 5MW9 chain E against the predicted model P54623: TM-score 0.93, RMSD 0.97 Å
- 5MW9 chain E against the predicted model P54623: TM-score 0.93, RMSD 0.97 Å
- 5MW9 chain A against the predicted model P54623: TM-score 0.92, RMSD 1.41 Å
- 5MW9 chain A against the predicted model P54623: TM-score 0.92, RMSD 1.41 Å
Elsewhere
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