UniProt P54284
Voltage-dependent L-type calcium channel subunit beta-3 (P54284)
Voltage-dependent L-type calcium channel subunit beta-3 (UniProt P54284): 20 experimental structures and 1 predicted model on GenesisL1, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P54284
- Protein
- Voltage-dependent L-type calcium channel subunit beta-3
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 30 · 16 records with a druggable one
Structures
21 records of P54284 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7MIX | Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom… | electron microscopy | C | — | 1 (best 0.77) |
| 7MIX | Human N-type voltage-gated calcium channel CAV2.2 in the presence of ziconotide at 3.0 ångström… | electron microscopy | C | — | — |
| 7MIY | Human N-type voltage-gated calcium channel Cav2.2 at 3.1 Angstrom resolution | electron microscopy | C | — | 1 (best 0.77) |
| 7MIY | Human N-type voltage-gated calcium channel CAV2.2 at 3.1 ångström resolution | electron microscopy | C | — | — |
| 7UHF | Human L-type voltage-gated calcium channel Cav1.3 in the presence of cinnarizine at 3.1 Angstrom… | electron microscopy | C | — | 1 (best 0.78) |
| 7UHF | Human L-type voltage-gated calcium channel CAV1.3 in the presence of cinnarizine at 3.1 ångström… | electron microscopy | C | — | — |
| 7UHG | Human L-type voltage-gated calcium channel Cav1.3 at 3.0 Angstrom resolution | electron microscopy | C | — | 1 (best 0.75) |
| 7UHG | Human L-type voltage-gated calcium channel CAV1.3 at 3.0 ångström resolution | electron microscopy | C | — | — |
| 8E59 | Human L-type voltage-gated calcium channel Cav1.3 in the presence of Amiodarone at 3.1 Angstrom… | electron microscopy | C | — | 2 (best 0.70) |
| 8E5A | Human L-type voltage-gated calcium channel Cav1.3 treated with 1.4 mM Sofosbuvir at 3.3 Angstrom… | electron microscopy | C | — | 1 (best 0.76) |
| 8E5B | Human L-type voltage-gated calcium channel Cav1.3 in the presence of Amiodarone and Sofosbuvir at… | electron microscopy | C | — | 3 (best 0.77) |
| 8EPL | Human R-type voltage-gated calcium channel Cav2.3 at 3.1 Angstrom resolution | electron microscopy | B | — | 1 (best 0.65) |
| 8FHS | Human L-type voltage-gated calcium channel Cav1.2 in the presence of amiodarone and sofosbuvir at… | electron microscopy | C | — | 3 (best 0.77) |
| 8WE6 | Human L-type voltage-gated calcium channel Cav1.2 at 2.9 Angstrom resolution | electron microscopy | C | — | 3 (best 0.75) |
| 8WE7 | Human L-type voltage-gated calcium channel Cav1.2 in the presence of calciseptine at 3.2 Angstrom… | electron microscopy | C | — | 3 (best 0.78) |
| 8WE8 | Human L-type voltage-gated calcium channel Cav1.2 in the presence of calciseptine, amlodipine and… | electron microscopy | C | — | 2 (best 0.78) |
| 8WE9 | Human L-type voltage-gated calcium channel Cav1.2 (Class I) in the presence of pinaverium at 3.0… | electron microscopy | C | — | 4 (best 0.75) |
| 8X90 | P/Q type calcium channel | electron microscopy | C | — | 2 (best 0.61) |
| 8X91 | P/Q type calcium channel in complex with omega-conotoxin MVIIC | electron microscopy | C | — | 1 (best 0.63) |
| 8X93 | P/Q type calcium channel in complex with omega-Agatoxin IVA | electron microscopy | C | — | 1 (best 0.61) |
| P54284 | AlphaFold monomer V2.0 prediction for voltage-dependent L-type calcium channel subunit beta-3… | predicted | A | — | — |
Experiment against prediction
- 7MIX chain C against the predicted model P54284: TM-score 0.87, RMSD 2.49 Å
- 7MIX chain C against the predicted model P54284: TM-score 0.87, RMSD 2.49 Å
- 8E5A chain C against the predicted model P54284: TM-score 0.87, RMSD 2.49 Å
- 8X93 chain C against the predicted model P54284: TM-score 0.87, RMSD 2.57 Å
- 7MIY chain C against the predicted model P54284: TM-score 0.87, RMSD 2.54 Å
- 7MIY chain C against the predicted model P54284: TM-score 0.87, RMSD 2.54 Å
- 8X90 chain C against the predicted model P54284: TM-score 0.87, RMSD 2.55 Å
- 8X91 chain C against the predicted model P54284: TM-score 0.87, RMSD 2.56 Å
- 8EPL chain B against the predicted model P54284: TM-score 0.87, RMSD 2.68 Å
- 7UHF chain C against the predicted model P54284: TM-score 0.87, RMSD 2.60 Å
Elsewhere
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