UniProt P53985
Monocarboxylate transporter 1 (P53985)
Monocarboxylate transporter 1 (UniProt P53985): 8 experimental structures on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P53985
- Protein
- Monocarboxylate transporter 1
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 2 · 1 record with a druggable one
Structures
8 records of P53985 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LYY | Cryo-EM structure of the human MCT1/BASIGIN-2 complex in the presence of anti-cancer drug candidate… | electron microscopy | A | EY0 | — |
| 6LZ0 | Cryo-EM structure of human MCT1 in complex with Basigin-2 in the presence of lactate | electron microscopy | A | 2OP | — |
| 6LZ0 | Cryo-EM structure of human MCT1 in complex with basigin-2 in the presence of lactate | electron microscopy | A | 2OP | — |
| 7CKO | Cryo-EM structure of the human MCT1/BASIGIN-2 complex in the presence of anti-cancer drug candidate… | electron microscopy | A | G5L | — |
| 7CKR | Cryo-EM structure of the human MCT1/BASIGIN-2 complex in the presence of anti-cancer drug candidate… | — | — | — | |
| 7DA5 | Cryo-EM structure of the human MCT1 D309N mutant in complex with basigin-2 in the inward-open… | electron microscopy | A | — | — |
| 7YR5 | Embigin facilitates monocarboxylate transporter 1 localization to plasma membrane and transition to… | electron microscopy | A | — | 2 (best 0.76) |
| P53985 | AlphaFold monomer V2.0 prediction for monocarboxylate transporter 1 (P53985) | — | — | — |
Ligands
- 2OP · (2S)-2-hydroxypropanoic acid · in 2 records
- EY0 · 3-methyl-5-[[(4~{R})-4-methyl-4-oxidanyl-1,2-oxazolidin-2-yl]carbonyl]-6-[[5-methyl-3-(trifluoromethyl)-1~{H}-pyrazol-4-yl]methyl]-1-propan-2-yl-thieno[2,3-d]pyrimidine-2,4-dione · in 1 record
- G5L · 7-[methyl-(phenylmethyl)amino]-2-oxidanylidene-chromene-3-carboxylic acid · in 1 record
Elsewhere
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