UniProt P53859
Exosome complex component CSL4 (P53859)
Exosome complex component CSL4 (UniProt P53859): 15 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P53859
- Protein
- Exosome complex component CSL4
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
16 records of P53859 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4IFD | Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA | x-ray diffraction | I | — | — |
| 4IFD | Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA | x-ray diffraction | I | — | — |
| 4OO1 | Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA | x-ray diffraction | I | — | — |
| 4OO1 | Structure of an RRP6-RNA exosome complex bound to POLY(A) RNA | x-ray diffraction | I | — | — |
| 5C0W | Structure of a 12-subunit nuclear exosome complex bound to single- stranded RNA substrates | x-ray diffraction | I | — | — |
| 5C0X | Structure of a 12-subunit nuclear exosome complex bound to structured RNA | x-ray diffraction | I | — | — |
| 5G06 | Cryo-EM structure of yeast cytoplasmic exosome | electron microscopy | I | — | — |
| 5G06 | Cryo-EM structure of yeast cytoplasmic exosome | electron microscopy | I | — | — |
| 5JEA | Structure of a cytoplasmic 11-subunit RNA exosome complex including SKI7, bound to RNA | x-ray diffraction | I | — | — |
| 5K36 | Structure of an eleven component nuclear RNA exosome complex bound to RNA | x-ray diffraction | I | SO4 | — |
| 5K36 | Structure of an eleven component nuclear RNA exosome complex bound to RNA | x-ray diffraction | I | SO4 | — |
| 5OKZ | Crystal strucrure of the MPP6 exosome complex | x-ray diffraction | m, I, S, c | — | — |
| 5VZJ | Structure of a twelve component MPP6-nuclear RNA exosome complex bound to RNA | x-ray diffraction | I | — | — |
| 6LQS | Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) | electron microscopy | C4 | — | — |
| 7AJT | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | electron microscopy | EJ | — | 1 (best 0.86) |
| P53859 | AlphaFold monomer V2.0 prediction for exosome complex component CSL4 (P53859) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 5OKZ chain m against the predicted model P53859: TM-score 0.90, RMSD 2.12 Å
- 4OO1 chain I against the predicted model P53859: TM-score 0.88, RMSD 2.24 Å
- 4OO1 chain I against the predicted model P53859: TM-score 0.88, RMSD 2.24 Å
- 5OKZ chain I against the predicted model P53859: TM-score 0.86, RMSD 2.55 Å
- 5K36 chain I against the predicted model P53859: TM-score 0.85, RMSD 2.40 Å
- 5K36 chain I against the predicted model P53859: TM-score 0.85, RMSD 2.40 Å
- 5VZJ chain I against the predicted model P53859: TM-score 0.85, RMSD 2.51 Å
- 5OKZ chain c against the predicted model P53859: TM-score 0.84, RMSD 2.55 Å
- 5C0W chain I against the predicted model P53859: TM-score 0.84, RMSD 2.68 Å
- 5OKZ chain S against the predicted model P53859: TM-score 0.84, RMSD 2.71 Å
Elsewhere
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