UniProt P53840
Topoisomerase 1-associated factor 1 (P53840)
Topoisomerase 1-associated factor 1 (UniProt P53840): 2 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P53840
- Protein
- Topoisomerase 1-associated factor 1
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 13 · 2 records with a druggable one
Structures
3 records of P53840 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6SKL | Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 | electron microscopy | X | — | 2 (best 0.87) |
| 8B9B | S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate… | electron microscopy | X | — | — |
| P53840 | AlphaFold monomer V2.0 prediction for topoisomerase 1-associated factor 1 (P53840) | predicted | A | — | 11 (best 0.78) |
Experiment against prediction
- 6SKL chain X against the predicted model P53840: TM-score 0.91, RMSD 3.12 Å
- 8B9B chain X against the predicted model P53840: TM-score 0.90, RMSD 3.15 Å
Elsewhere
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