UniProt P53136
Ribosome biogenesis protein NSA1 (P53136)
Ribosome biogenesis protein NSA1 (UniProt P53136): 18 experimental structures and 1 predicted model on GenesisL1, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P53136
- Protein
- Ribosome biogenesis protein NSA1
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 23 · 10 records with a druggable one
Structures
19 records of P53136 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5SUI | Ribosome assembly factor NSA1: C-terminal truncation | x-ray diffraction | A | — | — |
| 5SUM | Ribosome assembly factor NSA1 | x-ray diffraction | A, B | — | 4 (best 0.83) |
| 5SUM | Ribosome assembly factor NSA1 | x-ray diffraction | A, B | — | — |
| 5Z3G | Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) | electron microscopy | V | — | 1 (best 0.83) |
| 5Z3G | Cryo-EM structure of a nucleolar pre-60S ribosome (RPF1-tap) | electron microscopy | V | — | — |
| 6C0F | Yeast nucleolar pre-60S ribosomal subunit (state 2) | electron microscopy | A | — | — |
| 6C0F | Yeast nucleolar pre-60S ribosomal subunit (state 2) | electron microscopy | A | — | — |
| 6EM3 | State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | 5 | — | 4 (best 0.69) |
| 6EM3 | State a architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | 5 | — | — |
| 6EM4 | State B architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | 5 | — | — |
| 6EM5 | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | 5 | — | 1 (best 0.69) |
| 6EM5 | State D architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | 5 | — | — |
| 6EN7 | Crystal structure of the ribosome assembly factor Nsa1 | x-ray diffraction | A | — | 1 (best 0.78) |
| 6EN7 | Crystal structure of the ribosome assembly factor NSA1 | x-ray diffraction | A | — | — |
| 7OHS | Nog1-TAP associated immature ribosomal particle population F from S. cerevisiae | electron microscopy | 5 | — | 4 (best 0.84) |
| 7OHX | Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL34 expression shut… | electron microscopy | 5 | — | 3 (best 0.85) |
| 8V83 | 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) | electron microscopy | I | — | 2 (best 0.87) |
| 8V84 | 60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) | electron microscopy | I | — | 1 (best 0.86) |
| P53136 | AlphaFold monomer V2.0 prediction for ribosome biogenesis protein NSA1 (P53136) | predicted | A | — | 2 (best 0.79) |
Experiment against prediction
- 6EN7 chain A against the predicted model P53136: TM-score 0.99, RMSD 0.75 Å
- 6EN7 chain A against the predicted model P53136: TM-score 0.99, RMSD 0.75 Å
- 8V83 chain I against the predicted model P53136: TM-score 0.99, RMSD 1.03 Å
- 8V84 chain I against the predicted model P53136: TM-score 0.99, RMSD 1.01 Å
- 7OHX chain 5 against the predicted model P53136: TM-score 0.98, RMSD 1.08 Å
- 6EM5 chain 5 against the predicted model P53136: TM-score 0.98, RMSD 1.10 Å
- 6EM5 chain 5 against the predicted model P53136: TM-score 0.98, RMSD 1.10 Å
- 6EM4 chain 5 against the predicted model P53136: TM-score 0.98, RMSD 1.10 Å
- 6EM3 chain 5 against the predicted model P53136: TM-score 0.98, RMSD 1.10 Å
- 6EM3 chain 5 against the predicted model P53136: TM-score 0.98, RMSD 1.10 Å
Elsewhere
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