UniProt P52731
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (P52731)
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (UniProt P52731), EC 3.1.4.35: 4 experimental structures and 1 predicted model on GenesisL1, 21 pockets. Binding sites, druggability and experiment against…
- UniProt
- P52731
- Protein
- Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
- EC
- 3.1.4.35
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 21 · 2 records with a druggable one
Structures
5 records of P52731 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3DBA | Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C | x-ray diffraction | A, B | — | — |
| 3DBA | Crystal structure of the cgmp-bound gaf a domain from the photoreceptor phosphodiesterase 6C | x-ray diffraction | A, B | — | — |
| 6X88 | PDE6 chicken GAF domain | x-ray diffraction | A, B | — | 10 (best 0.71) |
| 6X88 | PDE6 chicken gaf domain | x-ray diffraction | A, B | — | — |
| P52731 | AlphaFold monomer V2.0 prediction for cone cgmp-specific 3',5'-cyclic phosphodiesterase subunit… | predicted | A | — | 11 (best 0.76) |
Experiment against prediction
- 6X88 chain B against the predicted model P52731: TM-score 0.96, RMSD 1.55 Å
- 6X88 chain B against the predicted model P52731: TM-score 0.96, RMSD 1.55 Å
- 6X88 chain A against the predicted model P52731: TM-score 0.95, RMSD 1.87 Å
- 6X88 chain A against the predicted model P52731: TM-score 0.95, RMSD 1.87 Å
- 3DBA chain A against the predicted model P52731: TM-score 0.93, RMSD 1.94 Å
- 3DBA chain A against the predicted model P52731: TM-score 0.93, RMSD 1.94 Å
Elsewhere
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