UniProt P51798
H(+)/Cl(-) exchange transporter 7 (P51798)
H(+)/Cl(-) exchange transporter 7 (UniProt P51798): 8 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 50 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P51798
- Protein
- H(+)/Cl(-) exchange transporter 7
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 50 · 3 records with a druggable one
Structures
9 records of P51798 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7BXU | Clc-7/OSTM1 membrane protein complex | electron microscopy | A, B | — | — |
| 7CQ5 | Structure of the human CLCN7-OSTM1 complex with ATP | electron microscopy | C, D | ATP, CL | 20 (best 0.82) |
| 7CQ5 | Structure of the human CLCN7-OSTM1 complex with ATP | electron microscopy | C, D | ATP, CL | — |
| 7CQ6 | Structure of the human CLCN7-OSTM1 complex | electron microscopy | C, D | CL | 20 (best 0.81) |
| 7CQ6 | Structure of the human CLCN7-OSTM1 complex | electron microscopy | C, D | CL | — |
| 7CQ7 | Structure of the human CLCN7-OSTM1 complex with ADP | electron microscopy | C, D | ADP, CL | — |
| 7JM7 | Structure of human clc-7/OSTM1 complex | electron microscopy | A, C | ATP, MG, CL, 0J1 | — |
| 8HVT | Structure of the human CLC-7/Ostm1 complex reveals a novel state | electron microscopy | A, C | — | 10 (best 0.85) |
| P51798 | AlphaFold monomer V2.0 prediction for H(+)/CL(-) exchange transporter 7 (P51798) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 6 records
- ATP · Adenosine-5'-triphosphate · in 3 records
- 0J1 · (2R)-3-{[(R)-hydroxy{[(1s,2r,3s,4s,5r,6r)-2,3,4,6-tetrahydroxy-5-(phosphonooxy) cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dinonanoate · in 1 record
- ADP · Adenosine-5'-diphosphate · in 1 record
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 8HVT chain C against the predicted model P51798: TM-score 0.98, RMSD 1.07 Å
- 8HVT chain A against the predicted model P51798: TM-score 0.98, RMSD 1.07 Å
- 7JM7 chain C against the predicted model P51798: TM-score 0.98, RMSD 1.44 Å
- 7JM7 chain A against the predicted model P51798: TM-score 0.98, RMSD 1.44 Å
- 7CQ6 chain D against the predicted model P51798: TM-score 0.98, RMSD 1.42 Å
- 7CQ6 chain D against the predicted model P51798: TM-score 0.98, RMSD 1.42 Å
- 7CQ6 chain C against the predicted model P51798: TM-score 0.98, RMSD 1.43 Å
- 7CQ6 chain C against the predicted model P51798: TM-score 0.98, RMSD 1.43 Å
- 7CQ7 chain C against the predicted model P51798: TM-score 0.97, RMSD 1.49 Å
- 7CQ7 chain D against the predicted model P51798: TM-score 0.97, RMSD 1.51 Å
Elsewhere
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