UniProt P50909
Tryptophan synthase beta chain 1 (P50909)
Tryptophan synthase beta chain 1 (UniProt P50909), EC 4.2.1.20: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P50909
- Protein
- Tryptophan synthase beta chain 1
- EC
- 4.2.1.20
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 3 records with a druggable one
Structures
3 records of P50909 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8EGZ | Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the… | x-ray diffraction | A, B | 0JO, K | 8 (best 0.81) |
| 8EH1 | Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the… | x-ray diffraction | A, B | 0JO, ES1, K | 9 (best 0.82) |
| P50909 | AlphaFold monomer V2.0 prediction for tryptophan synthase beta chain 1 (P50909) | predicted | A | — | 3 (best 0.78) |
Ligands
Experiment against prediction
- 8EH1 chain B against the predicted model P50909: TM-score 0.99, RMSD 0.63 Å
- 8EH1 chain A against the predicted model P50909: TM-score 0.99, RMSD 0.65 Å
- 8EGZ chain A against the predicted model P50909: TM-score 0.99, RMSD 0.75 Å
- 8EGZ chain B against the predicted model P50909: TM-score 0.99, RMSD 0.76 Å
Elsewhere
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