UniProt P49771
Fms-related tyrosine kinase 3 ligand (P49771)
Fms-related tyrosine kinase 3 ligand (UniProt P49771): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P49771
- Protein
- Fms-related tyrosine kinase 3 ligand
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 16 · 1 record with a druggable one
Structures
9 records of P49771 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ETE | Crystal structure of the FLT3 ligand | x-ray diffraction | A, B, C, D | — | — |
| 1ETE | Crystal structure of the FLT3 ligand | x-ray diffraction | A, B, C, D | — | — |
| 3QS7 | Crystal structure of a human Flt3 ligand-receptor ternary complex | x-ray diffraction | A, B, C, D | — | — |
| 3QS7 | Crystal structure of a human FLT3 ligand-receptor ternary complex | x-ray diffraction | A, B, C, D | — | — |
| 3QS9 | Crystal structure of a human Flt3 ligand-receptor ternary complex | x-ray diffraction | A, B, C, D | — | — |
| 3QS9 | Crystal structure of a human FLT3 ligand-receptor ternary complex | x-ray diffraction | A, B, C, D | — | — |
| 7NBI | Crystal structure of a monomeric FLT3 ligand variant | x-ray diffraction | A, B | SO4 | — |
| 7ZV9 | Crystal structure of FLT3 in complex with a monomeric FLT3 Ligand variant | x-ray diffraction | A, C, E, G, I, K, M, O | — | 16 (best 0.84) |
| P49771 | AlphaFold monomer V2.0 prediction for fms-related tyrosine kinase 3 ligand (P49771) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 3QS9 chain C against the predicted model P49771: TM-score 1.00, RMSD 0.27 Å
- 3QS9 chain C against the predicted model P49771: TM-score 1.00, RMSD 0.27 Å
- 3QS9 chain A against the predicted model P49771: TM-score 1.00, RMSD 0.27 Å
- 3QS9 chain A against the predicted model P49771: TM-score 1.00, RMSD 0.27 Å
- 3QS9 chain B against the predicted model P49771: TM-score 1.00, RMSD 0.27 Å
- 3QS9 chain B against the predicted model P49771: TM-score 1.00, RMSD 0.27 Å
- 3QS9 chain D against the predicted model P49771: TM-score 1.00, RMSD 0.27 Å
- 3QS9 chain D against the predicted model P49771: TM-score 1.00, RMSD 0.27 Å
- 3QS7 chain D against the predicted model P49771: TM-score 1.00, RMSD 0.28 Å
- 3QS7 chain D against the predicted model P49771: TM-score 1.00, RMSD 0.28 Å
Elsewhere
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