UniProt P49748
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (P49748)
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (UniProt P49748), EC 1.3.8.9: 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment…
- UniProt
- P49748
- Protein
- Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
- EC
- 1.3.8.9
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
6 records of P49748 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2UXW | Crystal structure of human very long chain acyl-CoA dehydrogenase (ACADVL) | x-ray diffraction | A | — | — |
| 2UXW | Crystal structure of human very long chain acyl-CoA dehydrogenase (acadvl) | x-ray diffraction | A | — | — |
| 3B96 | Structural Basis for Substrate Fatty-Acyl Chain Specificity: Crystal Structure of Human… | x-ray diffraction | A | — | — |
| 3B96 | Structural basis for substrate fatty-acyl chain specificity: crystal structure of human… | x-ray diffraction | A | — | — |
| 7S7G | Crystal Structure Analysis of Human VLCAD | x-ray diffraction | A | FAD | 5 (best 0.77) |
| P49748 | AlphaFold monomer V2.0 prediction for very long-chain specific acyl- CoA dehydrogenase… | predicted | A | — | — |
Ligands
- FAD · Flavin-adenine dinucleotide · in 1 record
Experiment against prediction
- 3B96 chain A against the predicted model P49748: TM-score 1.00, RMSD 0.19 Å
- 3B96 chain A against the predicted model P49748: TM-score 1.00, RMSD 0.19 Å
- 2UXW chain A against the predicted model P49748: TM-score 0.99, RMSD 0.98 Å
- 2UXW chain A against the predicted model P49748: TM-score 0.99, RMSD 0.98 Å
- 7S7G chain A against the predicted model P49748: TM-score 0.99, RMSD 1.20 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.