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UniProt P48995

Short transient receptor potential channel 1 (P48995)

Short transient receptor potential channel 1 (UniProt P48995): 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 39 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…

UniProt
P48995
Protein
Short transient receptor potential channel 1
Experimental structures
2
Predicted models
1
Ligands
4
Pockets
39 · 3 records with a druggable one

Structures

3 records of P48995 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
8WPLCryo-EM structure of the human TRPC1/C4 heteromerelectron microscopyALPP, ZN, Y0111 (best 0.85)
8WPMCryo-EM structure of the human TRPC1/C4 heteromer in complex with Pico145electron microscopyAPJQ, ZN12 (best 0.83)
P48995AlphaFold monomer V2.0 prediction for short transient receptor potential channel 1 (P48995)predictedA—16 (best 0.81)

Ligands

  • ZN · Zinc ion · in 2 records
  • LPP · 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate · in 1 record
  • PJQ · 7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)-8-[3-(trifluoromethyloxy) phenoxy]purine-2,6-dione · in 1 record
  • Y01 · Cholesterol hemisuccinate · in 1 record

Experiment against prediction

Elsewhere

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