UniProt P48645
Neuromedin-U-25 (P48645)
Neuromedin-U-25 (UniProt P48645): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P48645
- Protein
- Neuromedin-U-25
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 3 · 2 records with a druggable one
Structures
5 records of P48645 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7W53 | Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 1-gq protein complex | electron microscopy | C | — | — |
| 7W55 | Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 2-Gq protein complex | electron microscopy | C | — | 2 (best 0.77) |
| 7W55 | Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 2-gq protein complex | electron microscopy | C | — | — |
| 7XK8 | Cryo-EM structure of the Neuromedin U receptor 2 (NMUR2) in complex with G Protein and its… | electron microscopy | P | — | 1 (best 0.79) |
| P48645 | AlphaFold monomer V2.0 prediction for neuromedin-U (P48645) | predicted | A | — | — |
Experiment against prediction
- 7W55 chain C against the predicted model P48645: TM-score 0.56, RMSD 0.71 Å
- 7W55 chain C against the predicted model P48645: TM-score 0.56, RMSD 0.71 Å
- 7W53 chain C against the predicted model P48645: TM-score 0.51, RMSD 0.73 Å
- 7XK8 chain P against the predicted model P48645: TM-score 0.16, RMSD 3.75 Å
Elsewhere
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