UniProt P48542
G protein-activated inward rectifier potassium channel 2 (P48542)
G protein-activated inward rectifier potassium channel 2 (UniProt P48542): 12 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P48542
- Protein
- G protein-activated inward rectifier potassium channel 2
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
13 records of P48542 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E4F | Crystal Structure of the Cytoplasmic Domain of G-Protein-Gated Inward Rectifier Potassium Channel… | x-ray diffraction | A | — | — |
| 2E4F | Crystal structure of the cytoplasmic domain of G-protein-gated inward rectifier potassium channel… | x-ray diffraction | A | — | — |
| 3SYA | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with… | x-ray diffraction | A | — | — |
| 3SYA | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (KIR3.2) in complex with… | x-ray diffraction | A | — | — |
| 3SYC | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) D228N mutant | x-ray diffraction | A | — | — |
| 3SYC | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (KIR3.2) D228N mutant | x-ray diffraction | A | — | — |
| 3SYO | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with… | x-ray diffraction | A | — | — |
| 3SYO | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (KIR3.2) in complex with… | x-ray diffraction | A | — | — |
| 3SYP | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) R201A mutant | x-ray diffraction | A | — | — |
| 3SYP | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (KIR3.2) R201A mutant | x-ray diffraction | A | — | — |
| 3SYQ | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) R201A mutant in… | x-ray diffraction | A, B | — | — |
| 3SYQ | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (KIR3.2) R201A mutant in… | x-ray diffraction | A, B | — | — |
| P48542 | AlphaFold monomer V2.0 prediction for G protein-activated inward rectifier potassium channel 2… | predicted | A | — | 2 (best 0.43) |
Experiment against prediction
- 3SYA chain A against the predicted model P48542: TM-score 0.99, RMSD 0.76 Å
- 3SYA chain A against the predicted model P48542: TM-score 0.99, RMSD 0.76 Å
- 3SYO chain A against the predicted model P48542: TM-score 0.99, RMSD 0.79 Å
- 3SYO chain A against the predicted model P48542: TM-score 0.99, RMSD 0.79 Å
- 3SYC chain A against the predicted model P48542: TM-score 0.99, RMSD 0.80 Å
- 3SYC chain A against the predicted model P48542: TM-score 0.99, RMSD 0.80 Å
- 3SYP chain A against the predicted model P48542: TM-score 0.97, RMSD 1.14 Å
- 3SYP chain A against the predicted model P48542: TM-score 0.97, RMSD 1.14 Å
- 3SYQ chain B against the predicted model P48542: TM-score 0.95, RMSD 1.46 Å
- 3SYQ chain B against the predicted model P48542: TM-score 0.95, RMSD 1.46 Å
Elsewhere
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