UniProt P48059
LIM and senescent cell antigen-like-containing domain protein 1 (P48059)
LIM and senescent cell antigen-like-containing domain protein 1 (UniProt P48059): 25 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against…
- UniProt
- P48059
- Protein
- LIM and senescent cell antigen-like-containing domain protein 1
- Experimental structures
- 25
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
26 records of P48059 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1G47 | 1ST lim domain of pinch protein | solution nmr | A | — | — |
| 1G47 | 1ST lim domain of pinch protein | solution nmr | A | — | — |
| 1NYP | 4th LIM domain of PINCH protein | solution nmr | A | — | — |
| 1NYP | 4TH lim domain of pinch protein | solution nmr | A | — | — |
| 1U5S | NMR structure of the complex between Nck-2 SH3 domain and PINCH-1 LIM4 domain | solution nmr | B | — | — |
| 1U5S | NMR structure of the complex between nck-2 SH3 domain and pinch-1 LIM4 domain | solution nmr | B | — | — |
| 2COR | Solution structure of the third LIM domain of particularly interesting new Cys-His protein | solution nmr | A | — | — |
| 2COR | Solution structure of the third lim domain of particularly interesting new cys-his protein | solution nmr | A | — | — |
| 2D8X | Solution structure of the second LIM domain of particularly interesting new Cys-His protein (PINCH) | solution nmr | A | — | — |
| 2D8X | Solution structure of the second lim domain of particularly interesting new cys-his protein (pinch) | solution nmr | A | — | — |
| 2KBX | Solution structure of ILK-PINCH complex | solution nmr | B | — | — |
| 2KBX | Solution structure of ilk-pinch complex | solution nmr | B | — | — |
| 3F6Q | Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain | x-ray diffraction | B | — | — |
| 3F6Q | Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain | x-ray diffraction | B | — | — |
| 4HI8 | Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain… | x-ray diffraction | B | — | — |
| 4HI8 | Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain… | x-ray diffraction | B | — | — |
| 4HI9 | 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain… | x-ray diffraction | B | — | — |
| 4HI9 | 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain… | x-ray diffraction | B | — | — |
| 6MIF | Lim5 domain of PINCH1 protein | solution nmr | A | ZN | — |
| 6MIF | LIM5 domain of PINCH1 protein | solution nmr | A | ZN | — |
| 7D2S | Crystal structure of Rsu1/PINCH1_LIM5C complex | x-ray diffraction | B | ZN | 2 (best 0.72) |
| 7D2S | Crystal structure of RSU1/PINCH1_LIM5C complex | x-ray diffraction | B | ZN | — |
| 7D2T | Crystal structure of RSU1/PINCH1_LIM45C complex | x-ray diffraction | B, D | ZN | — |
| 7D2U | Crystal structure of RSU1/PINCH1_LIM45C complex | x-ray diffraction | B | ZN | — |
| 7LT9 | Crystal structure of RAS suppressor-1 in complex with pinch-1 LIM4-5 domains | x-ray diffraction | B | ZN | — |
| P48059 | AlphaFold monomer V2.0 prediction for lim and senescent cell antigen- like-containing domain… | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 7 records
Experiment against prediction
- 7D2S chain B against the predicted model P48059: TM-score 0.89, RMSD 1.14 Å
- 7D2S chain B against the predicted model P48059: TM-score 0.89, RMSD 1.14 Å
- 2D8X chain A against the predicted model P48059: TM-score 0.82, RMSD 1.79 Å
- 2D8X chain A against the predicted model P48059: TM-score 0.82, RMSD 1.79 Å
- 4HI8 chain B against the predicted model P48059: TM-score 0.80, RMSD 1.68 Å
- 4HI8 chain B against the predicted model P48059: TM-score 0.80, RMSD 1.68 Å
- 4HI9 chain B against the predicted model P48059: TM-score 0.80, RMSD 1.71 Å
- 4HI9 chain B against the predicted model P48059: TM-score 0.80, RMSD 1.71 Å
- 3F6Q chain B against the predicted model P48059: TM-score 0.79, RMSD 1.38 Å
- 3F6Q chain B against the predicted model P48059: TM-score 0.79, RMSD 1.38 Å
Elsewhere
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