UniProt P47929
Galectin-7 (P47929)
Galectin-7 (UniProt P47929): 43 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P47929
- Protein
- Galectin-7
- Experimental structures
- 43
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 14 · 1 record with a druggable one
Structures
44 records of P47929 in the MolNFT archive: 43 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BKZ | Crystal structure of human galectin-7 | x-ray diffraction | A, B | — | — |
| 1BKZ | Crystal structure of human galectin-7 | x-ray diffraction | A, B | — | — |
| 2GAL | Crystal structure of human galectin-7 in complex with galactose | x-ray diffraction | A, B | — | — |
| 2GAL | Crystal structure of human galectin-7 in complex with galactose | x-ray diffraction | A, B | — | — |
| 3GAL | Crystal structure of human galectin-7 in complex with galactosamine | x-ray diffraction | A, B | — | — |
| 3GAL | Crystal structure of human galectin-7 in complex with galactosamine | x-ray diffraction | A, B | — | — |
| 3ZXE | Crystal structure of Human Galectin-7 in complex with a galactose- benzylphosphate inhibitor | x-ray diffraction | A, B | — | — |
| 3ZXE | Crystal structure of human galectin-7 in complex with a galactose-benzylphosphate inhibitor | x-ray diffraction | A, B | — | — |
| 3ZXF | High resolution structure of Human Galectin-7 | x-ray diffraction | A, B | — | — |
| 3ZXF | High resolution structure of human galectin-7 | x-ray diffraction | A, B | — | — |
| 4GAL | Crystal structure of human galectin-7 in complex with lactose | x-ray diffraction | A, B | — | — |
| 4GAL | Crystal structure of human galectin-7 in complex with lactose | x-ray diffraction | A, B | — | — |
| 4UW3 | Human galectin-7 in complex with a galactose based dendron D1. | x-ray diffraction | A, B | — | — |
| 4UW3 | Human galectin-7 in complex with a galactose based dendron D1. | x-ray diffraction | A, B | — | — |
| 4UW4 | Human galectin-7 in complex with a galactose based dendron D2-1. | x-ray diffraction | A, B | — | — |
| 4UW4 | Human galectin-7 in complex with a galactose based dendron D2-1. | x-ray diffraction | A, B | — | — |
| 4UW5 | Human galectin-7 in complex with a galactose based dendron D2-2. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4UW5 | Human galectin-7 in complex with a galactose based dendron D2-2. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4UW6 | Human galectin-7 in complex with a galactose based dendron D3 | x-ray diffraction | A, B | — | — |
| 4UW6 | Human galectin-7 in complex with a galactose based dendron D3 | x-ray diffraction | A, B | — | — |
| 4XBQ | Crystal Structure of Human Galectin-7 in Complex with Type 1 N-acetyllactosamine | x-ray diffraction | A, B | — | — |
| 4XBQ | Crystal structure of human galectin-7 in complex with type 1 N- acetyllactosamine | x-ray diffraction | A, B | — | — |
| 4Y26 | Complex of human Galectin-7 and Galbeta1-3(6OSO3)GlcNAc | x-ray diffraction | A, B | — | — |
| 4Y26 | Complex of human galectin-7 and GALBETA1-3(6OSO3)GLCNAC | x-ray diffraction | A, B | — | — |
| 5GAL | Crystal structure of human galectin-7 in complex with N-acetyllactosamine | x-ray diffraction | A, B | NAG, GAL | 2 (best 0.30) |
| 5GAL | Crystal structure of human galectin-7 in complex with N- acetyllactosamine | x-ray diffraction | A, B | — | — |
| 5H9Q | Crystal Structure of Human Galectin-7 in Complex with TD139 | x-ray diffraction | A, B | TD2 | — |
| 5H9Q | Crystal structure of human galectin-7 in complex with TD139 | x-ray diffraction | A, B | — | — |
| 5H9S | Crystal Structure of Human Galectin-7 in Complex with TAZTDG | x-ray diffraction | A, B | TGZ | — |
| 5H9S | Crystal structure of human galectin-7 in complex with taztdg | x-ray diffraction | A, B | — | — |
| 6VTO | Crystal structure of human Galectin-7 in complex with 4-O-beta-D-Galactopyranosyl-D-glucose | x-ray diffraction | A, B | LBL | 2 (best 0.28) |
| 6VTO | Crystal structure of human galectin-7 in complex with 4-O-beta-D- galactopyranosyl-D-glucose | x-ray diffraction | A, B | LBL | — |
| 6VTP | Crystal structure of G16C human galectin-7 mutant | x-ray diffraction | A, B | — | — |
| 6VTQ | Crystal structure of G16C human galectin-7 mutant in complex with lactose | x-ray diffraction | A, B | GLC, GAL | — |
| 6VTR | Crystal structure of G16S human Galectin-7 mutant | x-ray diffraction | A, B | — | 1 (best 0.27) |
| 6VTR | Crystal structure of G16S human galectin-7 mutant | x-ray diffraction | A, B | — | — |
| 6VTS | Crystal structure of G16S human galectin-7 mutant in complex with lactose | x-ray diffraction | A, B | GLC, GAL | — |
| 7RDG | Crystal structure of D103A human Galectin-7 mutant in presence of lactose | x-ray diffraction | C, B, A, D | GLC, GAL | 6 (best 0.60) |
| 7TKX | Crystal structure of R14A human Galectin-7 mutant in presence of… | x-ray diffraction | A, B | LBL | — |
| 7TKY | Crystal structure of D94A human Galectin-7 mutant | x-ray diffraction | A, B | — | — |
| 7TKZ | Crystal structure of D94A human Galectin-7 mutant in presence of lactose | x-ray diffraction | B, A | GLC, GAL | 2 (best 0.27) |
| 7TRN | Crystal structure of R14A-R20A human Galectin-7 mutant | x-ray diffraction | A, B, C, D | — | — |
| 7XAC | Dimeric structure of human galectin-7 in complex with two glycerol | x-ray diffraction | A, B | — | 1 (best 0.30) |
| P47929 | AlphaFold monomer V2.0 prediction for galectin-7 (P47929) | predicted | A | — | — |
Ligands
- GAL · beta-D-galactopyranose · in 5 records
- GLC · alpha-D-glucopyranose · in 4 records
- LBL · (2~{R},3~{R},4~{R},5~{R})-4-[(2~{S},3~{R},4~{S},5~{R}, 6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-2,3,5, 6-tetrakis(oxidanyl)hexanal · in 3 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
- TD2 · 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside · in 1 record
- TGZ · (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol · in 1 record
Experiment against prediction
- 7TRN chain C against the predicted model P47929: TM-score 0.99, RMSD 0.32 Å
- 2GAL chain B against the predicted model P47929: TM-score 0.99, RMSD 0.32 Å
- 2GAL chain B against the predicted model P47929: TM-score 0.99, RMSD 0.32 Å
- 4UW5 chain A against the predicted model P47929: TM-score 0.99, RMSD 0.36 Å
- 4UW5 chain A against the predicted model P47929: TM-score 0.99, RMSD 0.36 Å
- 7TKY chain A against the predicted model P47929: TM-score 0.99, RMSD 0.37 Å
- 7TKY chain B against the predicted model P47929: TM-score 0.99, RMSD 0.36 Å
- 2GAL chain A against the predicted model P47929: TM-score 0.99, RMSD 0.38 Å
- 2GAL chain A against the predicted model P47929: TM-score 0.99, RMSD 0.38 Å
- 6VTR chain A against the predicted model P47929: TM-score 0.99, RMSD 0.41 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.