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UniProt P46948

Exosome complex component SKI6 (P46948)

Exosome complex component SKI6 (UniProt P46948): 16 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P46948
Protein
Exosome complex component SKI6
Experimental structures
16
Predicted models
1
Ligands
3
Pockets
2 · 0 records with a druggable one

Structures

17 records of P46948 in the MolNFT archive: 16 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
2WP8yeast rrp44 nucleasex-ray diffractionB——
2WP8Yeast RRP44 nucleasex-ray diffractionB——
4IFDCrystal structure of an 11-subunit eukaryotic exosome complex bound to RNAx-ray diffractionB——
4IFDCrystal structure of an 11-subunit eukaryotic exosome complex bound to RNAx-ray diffractionB——
4OO1Structure of an Rrp6-RNA exosome complex bound to poly(A) RNAx-ray diffractionB——
4OO1Structure of an RRP6-RNA exosome complex bound to POLY(A) RNAx-ray diffractionB——
5C0WStructure of a 12-subunit nuclear exosome complex bound to single- stranded RNA substratesx-ray diffractionB——
5C0XStructure of a 12-subunit nuclear exosome complex bound to structured RNAx-ray diffractionB——
5G06Cryo-EM structure of yeast cytoplasmic exosomeelectron microscopyB——
5G06Cryo-EM structure of yeast cytoplasmic exosomeelectron microscopyB——
5JEAStructure of a cytoplasmic 11-subunit RNA exosome complex including SKI7, bound to RNAx-ray diffractionB——
5K36Structure of an eleven component nuclear RNA exosome complex bound to RNAx-ray diffractionBSO4—
5K36Structure of an eleven component nuclear RNA exosome complex bound to RNAx-ray diffractionBSO4—
5OKZCrystal strucrure of the MPP6 exosome complexx-ray diffractionB, L, V, fTAM, CL—
5VZJStructure of a twelve component MPP6-nuclear RNA exosome complex bound to RNAx-ray diffractionBSO4—
6LQSCryo-EM structure of 90S small subunit preribosomes in transition states (State D)electron microscopyR1——
P46948AlphaFold monomer V2.0 prediction for exosome complex component SKI6 (P46948)predictedA—2 (best 0.43)

Ligands

  • SO4 · Sulfate ion · in 3 records
  • CL · Chloride ion · in 1 record
  • TAM · Tris(hydroxyethyl)aminomethane · in 1 record

Experiment against prediction

Elsewhere

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