UniProt P46935
E3 ubiquitin-protein ligase NEDD4 (P46935)
E3 ubiquitin-protein ligase NEDD4 (UniProt P46935): 2 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P46935
- Protein
- E3 ubiquitin-protein ligase NEDD4
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 10 · 1 record with a druggable one
Structures
3 records of P46935 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3M7F | Crystal structure of the Nedd4 C2/Grb10 SH2 complex | x-ray diffraction | B | — | — |
| 3M7F | Crystal structure of the NEDD4 C2/GRB10 SH2 complex | x-ray diffraction | B | — | — |
| P46935 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase NEDD4 (P46935) | predicted | A | — | 10 (best 0.76) |
Experiment against prediction
- 3M7F chain B against the predicted model P46935: TM-score 0.92, RMSD 1.08 Å
- 3M7F chain B against the predicted model P46935: TM-score 0.92, RMSD 1.08 Å
Elsewhere
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