UniProt P46531
Notch 1 extracellular truncation (P46531)
Notch 1 extracellular truncation (UniProt P46531): 45 experimental structures on GenesisL1, 2 ligands bound. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P46531
- Protein
- Notch 1 extracellular truncation
- Experimental structures
- 45
- Predicted models
- 0
- Ligands
- 2
Structures
45 records of P46531 in the MolNFT archive: 45 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PB5 | NMR Structure of a Prototype LNR Module from Human Notch1 | solution nmr | A | — | — |
| 1PB5 | NMR structure of a prototype lnr module from human NOTCH1 | solution nmr | A | — | — |
| 1TOZ | NMR structure of the human NOTCH-1 ligand binding region | solution nmr | A | — | — |
| 1TOZ | NMR structure of the human notch-1 ligand binding region | solution nmr | A | — | — |
| 1YYH | Crystal structure of the human Notch 1 ankyrin domain | x-ray diffraction | A, B | — | — |
| 1YYH | Crystal structure of the human notch 1 ankyrin domain | x-ray diffraction | A, B | — | — |
| 2F8X | Crystal structure of activated Notch, CSL and MAML on HES-1 promoter DNA sequence | x-ray diffraction | K | — | — |
| 2F8X | Crystal structure of activated notch, csl and maml on hes-1 promoter DNA sequence | x-ray diffraction | K | — | — |
| 2F8Y | Crystal structure of human Notch1 ankyrin repeats to 1.55A resolution. | x-ray diffraction | A, B | — | — |
| 2F8Y | Crystal structure of human NOTCH1 ankyrin repeats to 1.55A resolution. | x-ray diffraction | A, B | — | — |
| 2HE0 | Crystal structure of a human Notch1 ankyrin domain mutant | x-ray diffraction | A, B | — | — |
| 2HE0 | Crystal structure of a human NOTCH1 ankyrin domain mutant | x-ray diffraction | A, B | — | — |
| 2VJ3 | Human Notch-1 EGFs 11-13 | x-ray diffraction | A | — | — |
| 2VJ3 | Human notch-1 egfs 11-13 | x-ray diffraction | A | — | — |
| 3ETO | 2 Angstrom Xray structure of the NOTCH1 Negative Regulatory Region (NRR) | x-ray diffraction | A, B | — | — |
| 3ETO | 2 ångström xray structure of the NOTCH1 negative regulatory region (nrr) | x-ray diffraction | A, B | — | — |
| 3I08 | Crystal structure of the S1-cleaved Notch1 Negative Regulatory Region (NRR) | x-ray diffraction | A, B, C, D | — | — |
| 3I08 | Crystal structure of the S1-cleaved NOTCH1 negative regulatory region (nrr) | x-ray diffraction | A, B, C, D | — | — |
| 3L95 | Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of… | x-ray diffraction | X, Y | — | — |
| 3L95 | Crystal structure of the human NOTCH1 negative regulatory region (nrr) bound to the Fab fragment of… | x-ray diffraction | X, Y | — | — |
| 3NBN | Crystal structure of a dimer of Notch Transcription Complex trimers on HES1 DNA | x-ray diffraction | B, E | — | — |
| 3NBN | Crystal structure of a dimer of notch transcription complex trimers on HES1 DNA | x-ray diffraction | B, E | — | — |
| 3V79 | Structure of human Notch1 transcription complex including CSL, RAM, ANK, and MAML-1 on HES-1… | x-ray diffraction | K | — | — |
| 3V79 | Structure of human NOTCH1 transcription complex including csl, ram, ank, and maml-1 on hes-1… | x-ray diffraction | K | — | — |
| 4CUD | Human Notch1 EGF domains 11-13 mutant fucosylated at T466 | x-ray diffraction | A | — | — |
| 4CUD | Human NOTCH1 EGF domains 11-13 mutant fucosylated at T466 | x-ray diffraction | A | — | — |
| 4CUE | Human Notch1 EGF domains 11-13 mutant T466V | x-ray diffraction | A | — | — |
| 4CUE | Human NOTCH1 EGF domains 11-13 mutant T466V | x-ray diffraction | A | — | — |
| 4CUF | Human Notch1 EGF domains 11-13 mutant T466S | x-ray diffraction | A | — | — |
| 4CUF | Human NOTCH1 EGF domains 11-13 mutant T466S | x-ray diffraction | A | — | — |
| 4D0E | Human Notch1 EGF domains 11-13 mutant GlcNAc-fucose disaccharide modified at T466 | x-ray diffraction | A | — | — |
| 4D0E | Human NOTCH1 EGF domains 11-13 mutant glcnac-fucose disaccharide modified at T466 | x-ray diffraction | A | — | — |
| 4D0F | Human Notch1 EGF domains 11-13 mutant T466A | x-ray diffraction | A | — | — |
| 4D0F | Human NOTCH1 EGF domains 11-13 mutant T466A | x-ray diffraction | A | — | — |
| 5FM9 | Human notch 1, EGF 4-7 | x-ray diffraction | A | — | — |
| 5FMA | human Notch 1, EGF 4-7 | x-ray diffraction | A, B | CA, CL | — |
| 5FMA | Human notch 1, EGF 4-7 | x-ray diffraction | A, B | — | — |
| 5KZO | NOTCH1 transmembrane and associated juxtamembrane segment | solution nmr | A | — | — |
| 5L0R | human POGLUT1 in complex with Notch1 EGF12 and UDP | x-ray diffraction | B | CL, CA | — |
| 5L0R | Human POGLUT1 in complex with NOTCH1 EGF12 and udp | x-ray diffraction | B | CL, CA | — |
| 5UB5 | human POGLUT1 in complex with human Notch1 EGF12 S458T mutant and UDP | x-ray diffraction | B | CA | — |
| 5UB5 | Human POGLUT1 in complex with human NOTCH1 EGF12 S458T mutant and udp | x-ray diffraction | B | CA | — |
| 6PY8 | Crystal structure of the rbpj-NOTCH1-nrarp ternary complex bound to DNA | x-ray diffraction | F, K | — | — |
| 8ORY | Solution NMR structure of Notch1 L1740-1743 TMD | solution nmr | A | — | — |
| P46531 | AlphaFold monomer V2.0 prediction for neurogenic locus notch homolog protein 1 (P46531) | — | — | — |
Ligands
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.