UniProt P46098
5-hydroxytryptamine receptor 3A (P46098)
5-hydroxytryptamine receptor 3A (UniProt P46098): 1 experimental structure and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P46098
- Protein
- 5-hydroxytryptamine receptor 3A
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
2 records of P46098 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8BLA | Human serotonin 5-HT3A receptor in complex with vortioxetine (detergent, ECD only, active/distorted… | electron microscopy | A, B, C, D, E | NAG, VTX | 20 (best 0.75) |
| P46098 | AlphaFold monomer V2.0 prediction for 5-hydroxytryptamine receptor 3A (P46098) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8BLA chain C against the predicted model P46098: TM-score 0.99, RMSD 0.59 Å
- 8BLA chain B against the predicted model P46098: TM-score 0.99, RMSD 0.59 Å
- 8BLA chain D against the predicted model P46098: TM-score 0.99, RMSD 0.59 Å
- 8BLA chain A against the predicted model P46098: TM-score 0.99, RMSD 0.59 Å
- 8BLA chain E against the predicted model P46098: TM-score 0.99, RMSD 0.59 Å
Elsewhere
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