UniProt P46089
G-protein coupled receptor 3 (P46089)
G-protein coupled receptor 3 (UniProt P46089): 3 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P46089
- Protein
- G-protein coupled receptor 3
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 13 · 3 records with a druggable one
Structures
4 records of P46089 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8U8F | GPR3 Orphan G-coupled Protein Receptor in complex with Dominant Negative Gs. | electron microscopy | R | PLM | 3 (best 0.77) |
| 8WW2 | GPR3/Gs complex | electron microscopy | R | OLA, Y01, PLM | 4 (best 0.78) |
| 8X2K | OEA bound GPR3-Gs complex structure | electron microscopy | A | 5YM | 6 (best 0.76) |
| P46089 | AlphaFold monomer V2.0 prediction for G-protein coupled receptor 3 (P46089) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8X2K chain A against the predicted model P46089: TM-score 0.95, RMSD 1.49 Å
- 8U8F chain R against the predicted model P46089: TM-score 0.95, RMSD 1.52 Å
- 8WW2 chain R against the predicted model P46089: TM-score 0.94, RMSD 1.70 Å
- 8X2K chain A against the predicted model P0ABE7: TM-score 0.28, RMSD 4.65 Å
Elsewhere
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