UniProt P46087
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (P46087)
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (UniProt P46087), EC 2.1.1.-: 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P46087
- Protein
- Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase
- EC
- 2.1.1.-
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 3 · 3 records with a druggable one
Structures
5 records of P46087 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FKU | Human nucleolar pre-60S ribosomal subunit (State C2) | electron microscopy | SY | — | — |
| 8FKV | Human nucleolar pre-60S ribosomal subunit (State D1) | electron microscopy | SY | — | 1 (best 0.85) |
| 8FKW | Human nucleolar pre-60S ribosomal subunit (State D2) | electron microscopy | SY | — | 1 (best 0.85) |
| 8FKX | Human nucleolar pre-60S ribosomal subunit (State E) | electron microscopy | SY | — | — |
| P46087 | AlphaFold monomer V2.0 prediction for probable 28S rRNA (CYTOSINE(4447)-C(5))-methyltransferase… | predicted | A | — | 1 (best 0.57) |
Experiment against prediction
- 8FKV chain SY against the predicted model P46087: TM-score 0.98, RMSD 0.94 Å
- 8FKW chain SY against the predicted model P46087: TM-score 0.98, RMSD 0.95 Å
- 8FKU chain SY against the predicted model P46087: TM-score 0.98, RMSD 0.98 Å
- 8FKX chain SY against the predicted model P46087: TM-score 0.98, RMSD 1.02 Å
Elsewhere
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