UniProt P45956
CRISPR-associated endoribonuclease Cas2 (P45956)
CRISPR-associated endoribonuclease Cas2 (UniProt P45956), EC 3.1.-.-: 25 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 45 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P45956
- Protein
- CRISPR-associated endoribonuclease Cas2
- EC
- 3.1.-.-
- Experimental structures
- 25
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 45 · 5 records with a druggable one
Structures
26 records of P45956 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4MAK | Crystal structure of a putative ssRNA endonuclease Cas2, CRISPR adaptation protein from E.coli | x-ray diffraction | A, B | — | — |
| 4MAK | Crystal structure of a putative ssrna endonuclease CAS2, CRISPR adaptation protein from E.COLI | x-ray diffraction | A, B | — | — |
| 4P6I | Crystal structure of the Cas1-Cas2 complex from Escherichia coli | x-ray diffraction | A, B | — | — |
| 4P6I | Crystal structure of the CAS1-CAS2 complex from escherichia COLI | x-ray diffraction | A, B | — | — |
| 4QDL | Crystal structure of E.coli Cas1-Cas2 complex | x-ray diffraction | E, F | — | — |
| 4QDL | Crystal structure of E.COLI CAS1-CAS2 complex | x-ray diffraction | E, F | — | — |
| 5DLJ | Crystal Structure of Cas-DNA-N1 complex | x-ray diffraction | F, E | — | 6 (best 0.83) |
| 5DLJ | Crystal structure of CAS-DNA-N1 complex | x-ray diffraction | F, E | — | — |
| 5DQT | Crystal Structure of Cas-DNA-22 complex | x-ray diffraction | F, E, N, M | — | — |
| 5DQT | Crystal structure of CAS-DNA-22 complex | x-ray diffraction | F, E, N, M | — | — |
| 5DQU | Crystal Structure of Cas-DNA-10 complex | x-ray diffraction | E, F | — | 9 (best 0.81) |
| 5DQU | Crystal structure of CAS-DNA-10 complex | x-ray diffraction | E, F | — | — |
| 5DQZ | Crystal Structure of Cas-DNA-PAM complex | x-ray diffraction | F, E | — | — |
| 5DQZ | Crystal structure of CAS-DNA-pam complex | x-ray diffraction | F, E | — | — |
| 5DS4 | Crystal structure the Escherichia coli Cas1-Cas2 complex bound to protospacer DNA | x-ray diffraction | E, F | — | 10 (best 0.79) |
| 5DS4 | Crystal structure the escherichia COLI CAS1-CAS2 complex bound to protospacer DNA | x-ray diffraction | E, F | — | — |
| 5DS5 | Crystal structure the Escherichia coli Cas1-Cas2 complex bound to protospacer DNA and Mg | x-ray diffraction | E, F | MG | 10 (best 0.81) |
| 5DS5 | Crystal structure the escherichia COLI CAS1-CAS2 complex bound to protospacer DNA and mg | x-ray diffraction | E, F | — | — |
| 5DS6 | Crystal structure the Escherichia coli Cas1-Cas2 complex bound to protospacer DNA with splayed ends | x-ray diffraction | E, F | — | 10 (best 0.80) |
| 5DS6 | Crystal structure the escherichia COLI CAS1-CAS2 complex bound to protospacer DNA with splayed ends | x-ray diffraction | E, F | — | — |
| 5VVJ | CAS1-CAS2 bound to half-site intermediate | x-ray diffraction | E, F | — | — |
| 5VVK | CAS1-CAS2 bound to full-site mimic | x-ray diffraction | E, F | — | — |
| 5VVL | Cas1-Cas2 bound to full-site mimic with Ni | x-ray diffraction | E, F | — | — |
| 5VVL | CAS1-CAS2 bound to full-site mimic with ni | x-ray diffraction | E, F | — | — |
| 5WFE | CAS1-CAS2-ihf-DNA holo-complex | electron microscopy | E, F | — | — |
| P45956 | AlphaFold monomer V2.0 prediction for CRISPR-associated endoribonuclease CAS2 (P45956) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 5DLJ chain E against the predicted model P45956: TM-score 0.99, RMSD 0.28 Å
- 5DLJ chain E against the predicted model P45956: TM-score 0.99, RMSD 0.28 Å
- 5DLJ chain F against the predicted model P45956: TM-score 0.99, RMSD 0.29 Å
- 5DLJ chain F against the predicted model P45956: TM-score 0.99, RMSD 0.29 Å
- 5DQZ chain F against the predicted model P45956: TM-score 0.98, RMSD 0.49 Å
- 5DQZ chain F against the predicted model P45956: TM-score 0.98, RMSD 0.49 Å
- 5DQZ chain E against the predicted model P45956: TM-score 0.98, RMSD 0.50 Å
- 5DQZ chain E against the predicted model P45956: TM-score 0.98, RMSD 0.50 Å
- 5DQT chain M against the predicted model P45956: TM-score 0.98, RMSD 0.51 Å
- 5DQT chain M against the predicted model P45956: TM-score 0.98, RMSD 0.51 Å
Elsewhere
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