UniProt P43378
Tyrosine-protein phosphatase non-receptor type 9 (P43378)
Tyrosine-protein phosphatase non-receptor type 9 (UniProt P43378), EC 3.1.3.48: 14 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P43378
- Protein
- Tyrosine-protein phosphatase non-receptor type 9
- EC
- 3.1.3.48
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
15 records of P43378 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2PA5 | Crystal structure of human protein tyrosine phosphatase PTPN9 | x-ray diffraction | A, B | — | — |
| 2PA5 | Crystal structure of human protein tyrosine phosphatase PTPN9 | x-ray diffraction | A, B | — | — |
| 4GE2 | Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 3 | x-ray diffraction | A, B | — | — |
| 4GE2 | Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 3 | x-ray diffraction | A, B | — | — |
| 4GE5 | Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 5 | x-ray diffraction | A, B | — | — |
| 4GE5 | Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 5 | x-ray diffraction | A, B | — | — |
| 4GE6 | Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 7 | x-ray diffraction | A, B | — | — |
| 4GE6 | Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 7 | x-ray diffraction | A, B | — | — |
| 4ICZ | HER2 1221/1222 phosphorylation regulated by PTPN9 | x-ray diffraction | A | — | — |
| 4ICZ | HER2 1221/1222 phosphorylation regulated by PTPN9 | x-ray diffraction | A | — | — |
| 6KZQ | structure of PTP-MEG2 and NSF-pY83 peptide complex | x-ray diffraction | A | — | — |
| 6KZQ | Structure of ptp-MEG2 and nsf-PY83 peptide complex | x-ray diffraction | A | — | — |
| 6L03 | structure of PTP-MEG2 and MUNC18-1-pY145 peptide complex | x-ray diffraction | A | — | 2 (best 0.49) |
| 6L03 | Structure of ptp-MEG2 and MUNC18-1-PY145 peptide complex | x-ray diffraction | A | — | — |
| P43378 | AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type 9 (P43378) | predicted | A | — | 7 (best 0.81) |
Experiment against prediction
- 4GE5 chain A against the predicted model P43378: TM-score 1.00, RMSD 0.40 Å
- 4GE5 chain A against the predicted model P43378: TM-score 1.00, RMSD 0.40 Å
- 4GE2 chain A against the predicted model P43378: TM-score 1.00, RMSD 0.40 Å
- 4GE2 chain A against the predicted model P43378: TM-score 1.00, RMSD 0.40 Å
- 2PA5 chain A against the predicted model P43378: TM-score 0.99, RMSD 0.48 Å
- 2PA5 chain A against the predicted model P43378: TM-score 0.99, RMSD 0.48 Å
- 4GE2 chain B against the predicted model P43378: TM-score 0.99, RMSD 0.49 Å
- 4GE2 chain B against the predicted model P43378: TM-score 0.99, RMSD 0.49 Å
- 2PA5 chain B against the predicted model P43378: TM-score 0.99, RMSD 0.52 Å
- 2PA5 chain B against the predicted model P43378: TM-score 0.99, RMSD 0.52 Å
Elsewhere
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