UniProt P43166
P43166
P43166 (UniProt P43166): 15 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P43166
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 7
Structures
16 records of P43166 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3MDZ | Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7 | x-ray diffraction | A | — | — |
| 3MDZ | Crystal structure of human carbonic anhydrase VII [isoform 1], CA7 | x-ray diffraction | A | — | — |
| 3ML5 | Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide | x-ray diffraction | A | — | — |
| 3ML5 | Crystal structure of the C183S/C217S mutant of human ca VII in complex with acetazolamide | x-ray diffraction | A | — | — |
| 6G4T | The crystal structure of uninhibited C183S/C217S mutant of human ca VII | x-ray diffraction | A | ZN | — |
| 6H36 | The crystal structure of human carbonic anhydrase VII in complex with… | x-ray diffraction | A | ZN, FKE | — |
| 6H36 | The crystal structure of human carbonic anhydrase VII in complex with… | x-ray diffraction | A | ZN, FKE | — |
| 6H37 | The crystal structure of human carbonic anhydrase VII in complex with… | x-ray diffraction | A | ZN, FKQ | — |
| 6H37 | The crystal structure of human carbonic anhydrase VII in complex with… | x-ray diffraction | A | ZN, FKQ | — |
| 6H38 | The crystal structure of human carbonic anhydrase VII in complex with… | x-ray diffraction | A | ZN, FKK | — |
| 6H38 | The crystal structure of human carbonic anhydrase VII in complex with… | x-ray diffraction | A | ZN, FKK | — |
| 6SDT | Human carbonic anhydrase VII in complex with a sulfonamide inhibitor | x-ray diffraction | A | ZN, L8N | — |
| 6ZR9 | The crystal structure of the complex of hcavii with 2-(4… | x-ray diffraction | A | ZN | — |
| 7NC4 | Crystal structure of human carbonic anhydrase VII (hca VII) in complex with a… | x-ray diffraction | A | ZN, U7Z | — |
| 7P1A | Carbonic anhydrase VII sultam based inhibitors | x-ray diffraction | A | ZN, 4IQ | — |
| P43166 | AlphaFold monomer V2.0 prediction for carbonic anhydrase 7 (P43166) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 11 records
- FKE · 4-(4-phenylpiperidin-1-yl)carbonylbenzenesulfonamide · in 2 records
- FKK · 4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]carbonylbenzenesulfonamide · in 2 records
- FKQ · 4-(4-oxidanyl-4-phenyl-piperidin-1-yl) carbonylbenzenesulfonamide · in 2 records
- 4IQ · 4-[2-[4-[(4-methylphenyl)methyl]-1,1-bis(oxidanylidene)-1,2,4-thiadiazinan-2-yl]ethyl]benzenesulfonamide · in 1 record
- L8N · Phenyl-(4-sulfamoylphenoxy)phosphinic acid · in 1 record
- U7Z · 4-[4-(2-chlorophenyl)carbonylpiperazin-1-yl]carbonylbenzenesulfonamide · in 1 record
Experiment against prediction
- 6SDT chain A against the predicted model P43166: TM-score 1.00, RMSD 0.28 Å
- 7P1A chain A against the predicted model P43166: TM-score 1.00, RMSD 0.28 Å
- 6H38 chain A against the predicted model P43166: TM-score 1.00, RMSD 0.29 Å
- 6H38 chain A against the predicted model P43166: TM-score 1.00, RMSD 0.29 Å
- 6G4T chain A against the predicted model P43166: TM-score 1.00, RMSD 0.30 Å
- 7NC4 chain A against the predicted model P43166: TM-score 1.00, RMSD 0.30 Å
- 6H37 chain A against the predicted model P43166: TM-score 1.00, RMSD 0.31 Å
- 6H37 chain A against the predicted model P43166: TM-score 1.00, RMSD 0.31 Å
- 6H36 chain A against the predicted model P43166: TM-score 1.00, RMSD 0.33 Å
- 6H36 chain A against the predicted model P43166: TM-score 1.00, RMSD 0.33 Å
Elsewhere
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