UniProt P42943
T-complex protein 1 subunit eta (P42943)
T-complex protein 1 subunit eta (UniProt P42943): 17 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 43 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P42943
- Protein
- T-complex protein 1 subunit eta
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 43 · 6 records with a druggable one
Structures
18 records of P42943 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V81 | The crystal structure of yeast CCT reveals intrinsic asymmetry of eukaryotic cytosolic chaperonins | x-ray diffraction | G, O, g, o | — | — |
| 4V8R | The crystal structures of the eukaryotic chaperonin CCT reveal its functional partitioning | x-ray diffraction | AH, Ah, BH, Bh | — | — |
| 4V94 | Molecular architecture of the eukaryotic chaperonin TRiC/CCT derived by a combination of chemical… | x-ray diffraction | G, O, g, o | — | — |
| 5GW4 | Structure of yeast npp-tric | electron microscopy | h, H | — | — |
| 5GW5 | Structure of tric-AMP-pnp | electron microscopy | h, H | — | — |
| 6KRD | Tric at 0.05 mm ADP-alfx, conformation 4, 0.05-C4 | electron microscopy | h, H | — | — |
| 6KRE | TRiC at 0.05 mM ADP-AlFx, Conformation 2, 0.05-C2 | electron microscopy | h, H | — | — |
| 6KRE | Tric at 0.05 mm ADP-alfx, conformation 2, 0.05-C2 | electron microscopy | h, H | — | — |
| 6KS6 | Tric at 0.2 mm ADP-alfx, conformation 1, 0.2-C1 | electron microscopy | h, H | ADP, MG, AF3 | — |
| 6KS7 | TRiC at 0.1 mM ADP-AlFx, Conformation 1, 0.1-C1 | electron microscopy | H, h | — | 9 (best 0.86) |
| 6KS7 | Tric at 0.1 mm ADP-alfx, conformation 1, 0.1-C1 | electron microscopy | H, h | — | — |
| 6KS8 | Tric at 0.1 mm ADP-alfx, conformation 4, 0.1-C4 | electron microscopy | h, H | — | — |
| 7YLU | yeast TRiC-plp2-substrate complex at S1 TRiC-NPP state | electron microscopy | H, h | — | — |
| 7YLV | yeast TRiC-plp2-substrate complex at S2 ATP binding state | electron microscopy | H, h | — | 6 (best 0.85) |
| 7YLW | yeast TRiC-plp2-tubulin complex at S3 closed TRiC state | electron microscopy | H, h | ADP, MG, AF3 | 7 (best 0.88) |
| 7YLX | yeast TRiC-plp2-actin complex at S4 closed TRiC state | electron microscopy | H, h | ADP, MG, AF3 | 9 (best 0.90) |
| 7YLY | yeast TRiC-plp2 complex at S5 closed TRiC state | electron microscopy | H, h | ADP, MG, AF3 | 8 (best 0.90) |
| P42943 | AlphaFold monomer V2.0 prediction for T-complex protein 1 subunit eta (P42943) | predicted | A | — | 4 (best 0.77) |
Ligands
Experiment against prediction
- 4V8R chain AH against the predicted model P42943: TM-score 0.96, RMSD 1.71 Å
- 4V94 chain G against the predicted model P42943: TM-score 0.95, RMSD 1.87 Å
- 6KS6 chain h against the predicted model P42943: TM-score 0.95, RMSD 1.92 Å
- 6KS6 chain H against the predicted model P42943: TM-score 0.95, RMSD 1.93 Å
- 7YLW chain h against the predicted model P42943: TM-score 0.95, RMSD 1.88 Å
- 7YLX chain h against the predicted model P42943: TM-score 0.95, RMSD 2.00 Å
- 7YLY chain h against the predicted model P42943: TM-score 0.95, RMSD 2.00 Å
- 7YLW chain H against the predicted model P42943: TM-score 0.95, RMSD 1.97 Å
- 7YLX chain H against the predicted model P42943: TM-score 0.95, RMSD 2.02 Å
- 7YLY chain H against the predicted model P42943: TM-score 0.95, RMSD 2.02 Å
Elsewhere
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