UniProt P42898
Methylenetetrahydrofolate reductase (NADPH) (P42898)
Methylenetetrahydrofolate reductase (NADPH) (UniProt P42898): 4 experimental structures on GenesisL1, 3 ligands bound, 25 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P42898
- Protein
- Methylenetetrahydrofolate reductase (NADPH)
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 25 · 2 records with a druggable one
Structures
4 records of P42898 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6FCX | Structure of human 5,10-methylenetetrahydrofolate reductase (mthfr) | x-ray diffraction | A, B | FAD | — |
| 8QA5 | MTHFR + SAH asymmetric dis-inhibited state | electron microscopy | A, B | FAD, SAH | 11 (best 0.64) |
| 8QA6 | MTHFR + SAM inhibited state | electron microscopy | A, B | SAM, FAD | 14 (best 0.83) |
| P42898 | AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate reductase (P42898) | — | — | — |
Ligands
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.