UniProt P42081
T-lymphocyte activation antigen CD86 (P42081)
T-lymphocyte activation antigen CD86 (UniProt P42081): 8 experimental structures and 1 predicted model on GenesisL1, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P42081
- Protein
- T-lymphocyte activation antigen CD86
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 30 · 3 records with a druggable one
Structures
9 records of P42081 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1I85 | Crystal structure of the ctla-4/B7-2 complex | x-ray diffraction | A, B | — | — |
| 1I85 | Crystal structure of the ctla-4/B7-2 complex | x-ray diffraction | A, B | — | — |
| 1NCN | the receptor-binding domain of human B7-2 | x-ray diffraction | A, B | — | — |
| 1NCN | The receptor-binding domain of human B7-2 | x-ray diffraction | A, B | — | — |
| 5YXK | High resolution crystal structure of Human B7-2 IgV domain in P21 space group | x-ray diffraction | A, B, C, D | — | 3 (best 0.62) |
| 5YXK | High resolution crystal structure of human B7-2 igv domain in P21 space group | x-ray diffraction | A, B, C, D | — | — |
| 8HXB | Cryo-EM structure of MPXV M2 hexamer in complex with human B7.2 | electron microscopy | G, H, I, J, K, L | — | 11 (best 0.72) |
| 8HXC | Cryo-EM structure of MPXV M2 heptamer in complex with human B7.2 | electron microscopy | H, I, J, K, L, M, N | — | 16 (best 0.70) |
| P42081 | AlphaFold monomer V2.0 prediction for T-lymphocyte activation antigen CD86 (P42081) | predicted | A | — | — |
Experiment against prediction
- 1I85 chain B against the predicted model P42081: TM-score 0.98, RMSD 0.57 Å
- 1I85 chain B against the predicted model P42081: TM-score 0.98, RMSD 0.57 Å
- 1NCN chain B against the predicted model P42081: TM-score 0.97, RMSD 0.72 Å
- 1NCN chain B against the predicted model P42081: TM-score 0.97, RMSD 0.72 Å
- 1I85 chain A against the predicted model P42081: TM-score 0.97, RMSD 0.68 Å
- 1I85 chain A against the predicted model P42081: TM-score 0.97, RMSD 0.68 Å
- 1NCN chain A against the predicted model P42081: TM-score 0.97, RMSD 0.73 Å
- 1NCN chain A against the predicted model P42081: TM-score 0.97, RMSD 0.73 Å
- 5YXK chain C against the predicted model P42081: TM-score 0.97, RMSD 0.80 Å
- 5YXK chain C against the predicted model P42081: TM-score 0.97, RMSD 0.80 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.