UniProt P40939
Trifunctional enzyme subunit alpha, mitochondrial (P40939)
Trifunctional enzyme subunit alpha, mitochondrial (UniProt P40939), EC 1.1.1.211, 4.2.1.17: 4 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P40939
- Protein
- Trifunctional enzyme subunit alpha, mitochondrial
- EC
- 1.1.1.211, 4.2.1.17
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 16 · 1 record with a druggable one
Structures
5 records of P40939 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZQZ | Structure of human mitochondrial trifunctional protein, tetramer | electron microscopy | A, C | — | 16 (best 0.83) |
| 5ZQZ | Structure of human mitochondrial trifunctional protein, tetramer | electron microscopy | A, C | — | — |
| 5ZRV | Structure of human mitochondrial trifunctional protein, octamer | electron microscopy | A, C, E, G | — | — |
| 6DV2 | Crystal structure of human mitochondrial trifunctional protein | x-ray diffraction | G, H, I, J, K, L | — | — |
| P40939 | AlphaFold monomer V2.0 prediction for trifunctional enzyme subunit alpha, mitochondrial (P40939) | predicted | A | — | — |
Experiment against prediction
- 6DV2 chain J against the predicted model P40939: TM-score 0.98, RMSD 1.53 Å
- 6DV2 chain L against the predicted model P40939: TM-score 0.97, RMSD 1.54 Å
- 6DV2 chain I against the predicted model P40939: TM-score 0.97, RMSD 1.54 Å
- 6DV2 chain K against the predicted model P40939: TM-score 0.97, RMSD 1.55 Å
- 6DV2 chain H against the predicted model P40939: TM-score 0.97, RMSD 1.58 Å
- 6DV2 chain G against the predicted model P40939: TM-score 0.97, RMSD 1.66 Å
- 5ZRV chain C against the predicted model P40939: TM-score 0.96, RMSD 1.81 Å
- 5ZQZ chain C against the predicted model P40939: TM-score 0.96, RMSD 1.81 Å
- 5ZQZ chain C against the predicted model P40939: TM-score 0.96, RMSD 1.81 Å
- 5ZRV chain G against the predicted model P40939: TM-score 0.96, RMSD 1.81 Å
Elsewhere
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