UniProt P40711
Peptidyl-tRNA hydrolase ArfB (P40711)
Peptidyl-tRNA hydrolase ArfB (UniProt P40711), EC 3.1.1.29: 8 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40711
- Protein
- Peptidyl-tRNA hydrolase ArfB
- EC
- 3.1.1.29
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 14 · 5 records with a druggable one
Structures
9 records of P40711 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2RTX | Solution structure of the GGQ domain of YaeJ protein from Escherichia coli | solution nmr | A | — | — |
| 2RTX | Solution structure of the ggq domain of yaej protein from escherichia COLI | solution nmr | A | — | — |
| 4V95 | Crystal structure of YAEJ bound to the 70S ribosome | x-ray diffraction | AY | — | — |
| 7JSS | ArfB Rescue of a 70S Ribosome stalled on truncated mRNA with a partial A-site codon (+2-II) | electron microscopy | 8 | — | 3 (best 0.88) |
| 7JSZ | ArfB Rescue of a 70S Ribosome stalled on truncated mRNA with a partial A-site codon (+2-IV) | electron microscopy | 8 | — | 1 (best 0.86) |
| 7JT1 | 70S ribosome stalled on long mRNA with ArfB-1 and ArfB-2 bound (+9-III) | electron microscopy | 8, 9 | — | 4 (best 0.87) |
| 7JT2 | 70S ribosome stalled on long mRNA with ArfB bound in the A site | electron microscopy | 8 | — | 4 (best 0.87) |
| 7JT3 | Rotated 70S ribosome stalled on long mRNA with ArfB-1 and ArfB-2 bound in the A site (+9-IV) | electron microscopy | 8, 9 | — | 2 (best 0.87) |
| P40711 | AlphaFold monomer V2.0 prediction for peptidyl-tRNA hydrolase arfb (P40711) | predicted | A | — | — |
Experiment against prediction
- 7JT1 chain 9 against the predicted model P40711: TM-score 0.78, RMSD 2.06 Å
- 4V95 chain AY against the predicted model P40711: TM-score 0.78, RMSD 2.33 Å
- 7JSS chain 8 against the predicted model P40711: TM-score 0.77, RMSD 2.30 Å
- 7JT2 chain 8 against the predicted model P40711: TM-score 0.76, RMSD 2.38 Å
- 7JT1 chain 8 against the predicted model P40711: TM-score 0.74, RMSD 2.48 Å
- 7JT3 chain 9 against the predicted model P40711: TM-score 0.73, RMSD 2.69 Å
- 7JT3 chain 8 against the predicted model P40711: TM-score 0.73, RMSD 2.88 Å
- 2RTX chain A against the predicted model P40711: TM-score 0.72, RMSD 1.97 Å
- 2RTX chain A against the predicted model P40711: TM-score 0.72, RMSD 1.97 Å
- 7JSZ chain 8 against the predicted model P40711: TM-score 0.67, RMSD 1.62 Å
Elsewhere
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