UniProt P40540

ER membrane protein complex subunit 5 (P40540)

ER membrane protein complex subunit 5 (UniProt P40540): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P40540
Protein: ER membrane protein complex subunit 5
Experimental structures: 5
Predicted models: 1
Ligands: 1
Pockets: 11 · 2 records with a druggable one

Structures

6 records of P40540 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6WB9	Structure of the S. cerevisiae ER membrane complex	electron microscopy	5	POV	6 (best 0.72)
6WB9	Structure of the S. cerevisiae er membrane complex	electron microscopy	5	POV	—
7KRA	Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to Fab-DH4 in lipid…	electron microscopy	E	—	5 (best 0.73)
7KRA	Cryo-EM structure of saccharomyces cerevisiae er membrane protein complex bound to Fab-DH4 in lipid…	electron microscopy	E	—	—
7KTX	Cryo-EM structure of saccharomyces cerevisiae er membrane protein complex bound to a Fab in ddm…	electron microscopy	E	—	—
P40540	AlphaFold monomer V2.0 prediction for er membrane protein complex subunit 5 (P40540)	predicted	A	—	—

Ligands

POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · in 2 records

Experiment against prediction

6WB9 chain 5 against the predicted model P40540: TM-score 0.52, RMSD 3.20 Å
6WB9 chain 5 against the predicted model P40540: TM-score 0.52, RMSD 3.20 Å
7KRA chain E against the predicted model P40540: TM-score 0.51, RMSD 3.33 Å
7KRA chain E against the predicted model P40540: TM-score 0.51, RMSD 3.33 Å
7KTX chain E against the predicted model P40540: TM-score 0.48, RMSD 3.75 Å

Elsewhere

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