UniProt P40306
P40306
P40306 (UniProt P40306): 26 experimental structures on GenesisL1, 15 ligands bound. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P40306
- Experimental structures
- 26
- Predicted models
- 0
- Ligands
- 15
Structures
26 records of P40306 in the MolNFT archive: 26 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AVO | Cryo-EM structure of human immunoproteasome with a novel noncompetitive inhibitor that selectively… | electron microscopy | B, E | — | — |
| 6E5B | Human Immunoproteasome 20S particle in complex with compound 1 | x-ray diffraction | H, V | NA | — |
| 6E5B | Human immunoproteasome 20S particle in complex with compound 1 | x-ray diffraction | H, V | NA | — |
| 6HV3 | Yeast 20S proteasome with human beta2i (1-53) | x-ray diffraction | H, V | CL, SO4, MG | — |
| 6HV3 | Yeast 20S proteasome with human BETA2I (1-53) | x-ray diffraction | H, V | CL, SO4, MG | — |
| 6HV4 | Yeast 20S proteasome with human beta2i (1-53) in complex with ONX 0914 | x-ray diffraction | H, V | CL, GQK, MG | — |
| 6HV4 | Yeast 20S proteasome with human BETA2I (1-53) in complex with onx 0914 | x-ray diffraction | H, V | CL, GQK, MG | — |
| 6HV5 | Yeast 20S proteasome with human beta2i (1-53) in complex with 4 | x-ray diffraction | H, V | CL, GQH, MG | — |
| 6HV5 | Yeast 20S proteasome with human BETA2I (1-53) in complex with 4 | x-ray diffraction | H, V | CL, GQH, MG | — |
| 6HV7 | Yeast 20S proteasome with human beta2i (1-53) in complex with 7 | x-ray diffraction | H, V | CL, GQQ, MG | — |
| 6HV7 | Yeast 20S proteasome with human BETA2I (1-53) in complex with 7 | x-ray diffraction | H, V | CL, GQQ, MG | — |
| 6HVA | Yeast 20S proteasome with human BETA2I (1-53) in complex with 13 | x-ray diffraction | H, V | CL, GQT, MG | — |
| 6HVR | Yeast 20S proteasome with human BETA2I (1-53) in complex with 16 | x-ray diffraction | H, V | CL, GRW, MG | — |
| 6HVS | Yeast 20S proteasome with human beta2i (1-53) in complex with 18 | x-ray diffraction | H, V | CL, GRT, MG | — |
| 6HVS | Yeast 20S proteasome with human BETA2I (1-53) in complex with 18 | x-ray diffraction | H, V | CL, GRT, MG | — |
| 6HVT | Yeast 20S proteasome with human beta2i (1-53) in complex with 20 | x-ray diffraction | H, V | CL, GT5, MG | — |
| 6HVT | Yeast 20S proteasome with human BETA2I (1-53) in complex with 20 | x-ray diffraction | H, V | CL, GT5, MG | — |
| 6HVU | Yeast 20S proteasome with human beta2i (1-53) in complex with 29 | x-ray diffraction | H, V | CL, GTW, MG | — |
| 6HVU | Yeast 20S proteasome with human BETA2I (1-53) in complex with 29 | x-ray diffraction | H, V | CL, GTW, MG | — |
| 6HVV | Yeast 20S proteasome with human beta2i (1-53) in complex with 39 | x-ray diffraction | H, V | CL, GT8, MG | — |
| 6HVV | Yeast 20S proteasome with human BETA2I (1-53) in complex with 39 | x-ray diffraction | H, V | CL, GT8, MG | — |
| 6HVW | Yeast 20S proteasome with human BETA2I (1-53) in complex with 43 | x-ray diffraction | H, V | CL, GVW, MG | — |
| 7AWE | Human immunoproteasome 20S particle in complex with [(1R)-2-(1… | x-ray diffraction | I, W | NA | — |
| 7B12 | HUMAN IMMUNOPROTEASOME 20S PARTICLE IN COMPLEX WITH… | x-ray diffraction | i, w | SKN, NA | — |
| 7B12 | Human immunoproteasome 20S particle in complex with [2-(3… | x-ray diffraction | i, w | SKN, NA | — |
| P40306 | AlphaFold monomer V2.0 prediction for proteasome subunit beta type-10 (P40306) | — | — | — |
Ligands
- CL · Chloride ion · in 19 records
- MG · Magnesium ion · in 19 records
- NA · Sodium ion · in 5 records
- GQH · (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl) phenyl]-4-methylsulfonyl-butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide · in 2 records
- GQK · (2~{S})-3-(4-methoxyphenyl)-~{N}-[(2~{S},3~{R})-4-methyl-3,4-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino) propanoyl]amino]propanamide · in 2 records
- GQQ · ~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]pyrazine-2-carboxamide · in 2 records
- GRT · (2~{S})-~{N}-[2-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-2-oxidanylidene-ethyl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide · in 2 records
- GT5 · ~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide · in 2 records
- GT8 · (2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino) propanoyl]amino]propanamide · in 2 records
- GTW · ~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-cyclohexyl-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide · in 2 records
- SKN · ((R)-2-(3-ethylphenyl)-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)ethyl)boronic acid · in 2 records
- SO4 · Sulfate ion · in 2 records
- GQT · (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl) phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide · in 1 record
- GRW · (2~{S})-~{N}-[(2~{S},3~{R})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-butan-2-yl]-2-[[(2~{R})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide · in 1 record
- GVW · (2~{S})-~{N}-[(2~{S},3~{R})-1-[(4~{A}~{S},8~{A}~{S})-1, 2,3,4,4~{A},5,6,7,8,8~{A}-decahydronaphthalen-2-yl]-4-methyl-3,4-bis(oxidanyl)pentan-2-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide · in 1 record
Elsewhere
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